Okadaic acid

Also known as: Halochondrine A, 9,10-Deepithio-9,10-didehydroacanthifolicin, 35-Demethyldinophysistoxin 1, NSC 677083, OA, (2R)-2-Hydroxy-3-[(2S,5R,6R,8S)-5-hydroxy-8-{(2R,3E)-4-[(2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylenecotahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl]-3-buten-2-yl}-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-methylpropanoic acid

Okadaic acid (CAS 78111-17-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C44H68O13 and a molecular weight of 805.003 g/mol. Key properties include a melting point of 164-166ºC, a boiling point of 921.6±65.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 269.4±27.8 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H311 — Toxic in contact with skin and H331 — Toxic if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 78111-17-8
Jingsj CID: J-15298-5
Molecular Formula: C₄₄H₆₈O₁₃
Molecular Weight: 805.003 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	164-166ºC
Boiling Point	921.6±65.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	269.4±27.8 °C
Exact Mass	804.466003
PSA	182.83000
LogP	4.21
Vapor Pressure	0.0±0.6 mmHg at 25°C
Refractive Index	1.585

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H301 — Toxic if swallowed
H311 — Toxic in contact with skin
H331 — Toxic if inhaled
H315 — Causes skin irritation

Activity & Biological Data

Target	IC50: 10-15 nM (PP1), 0.5 nM (PP2) and 4 nM (PP3)[1]
Additional Information	[1]. Bialojan C, et al. Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics. Biochem J. 1988 Nov 15;256(1):283-90. [2]. McCluskey A, et al. Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies. J Med Chem. 2002 Mar 14;45(6):1151-75. [3]. Schröder HC, et al. Okadaic acid, an apoptogenic toxin for symbiotic/parasitic annelids in the demosponge Suberites domuncula. Appl Environ Microbiol. 2006 Jul;72(7):4907-16.

Target

IC50: 10-15 nM (PP1), 0.5 nM (PP2) and 4 nM (PP3)[1]

Additional Information

[1]. Bialojan C, et al. Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics. Biochem J. 1988 Nov 15;256(1):283-90. [2]. McCluskey A, et al. Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies. J Med Chem. 2002 Mar 14;45(6):1151-75. [3]. Schröder HC, et al. Okadaic acid, an apoptogenic toxin for symbiotic/parasitic annelids in the demosponge Suberites domuncula. Appl Environ Microbiol. 2006 Jul;72(7):4907-16.

Frequently Asked Questions

What is the CAS number of Okadaic acid?

The CAS number of Okadaic acid is 78111-17-8.

What are the molecular formula and molecular weight of Okadaic acid?

Okadaic acid has molecular formula C44H68O13 and molecular weight 805.003 g/mol.

Is Okadaic acid hazardous?

Okadaic acid has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H311 — Toxic in contact with skin; H331 — Toxic if inhaled.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Okadaic acid (CAS 78111-17-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-15298-5 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.