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ethyl 2-(2,6-dichloro-5-fluoronicotinoyl)-3-((2,4-difluorophenyl)amino)acrylate

Also known as: 2,6-Dichloro-alpha-[[(2,4-difluorophenyl)amino]methylene]-5-fluoro-beta-oxo-3-pyridinepropanoic acid ethyl ester, 3-Pyridinepropanoic acid, 2,6-dichloro-α-[[(2,4-difluorophenyl)amino]methylene]-5-fluoro-β-oxo-, ethyl ester, Ethyl 2-(2,6-dichlor-5-fluorpyridin-3-carbonyl)-3-(2,4-difluorphenylamino)acrylate, Ethyl 2-(2,6-dichloro-5-fluoropyridin-3-carbonyl)-3-(2,4-difluorphenylamino)acrylate, Ethyl3-(2,4-Difluoroanilino)-2-(2,6-dichloro-5-fluronicotinoyl)acrylate, ethyl (E)-2-(2,6-dichloro-5-fluoropyridine-3-carbonyl)-3-(2,4-difluoroanilino)prop-2-enoate, ethyl 2-(2,6-dichloro-5-fluoronicotinoyl)-3-((2,4-difluorophenyl)amino)acrylate, ethyl(E)-2-(2,6-dichloro-5-fluoropyridine-3-carbonyl)-3-(2,4-difluoroanilino)prop-2-enoate

ethyl 2-(2,6-dichloro-5-fluoronicotinoyl)-3-((2,4-difluorophenyl)amino)acrylate (CAS 100490-99-1) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C17H11Cl2F3N2O3 and a molecular weight of 419.18200 g/mol. Key properties include a melting point of 138-139℃ and a density of 1.510. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
100490-99-1
Jingsj CID
J-1526567-5
Molecular Formula
C17H11Cl2F3N2O3
Molecular Weight
419.18200 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point138-139℃
Density1.510
Exact Mass418.01000
PSA68.29000
LogP4.62050

Customs & Trade Information

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of ethyl 2-(2,6-dichloro-5-fluoronicotinoyl)-3-((2,4-difluorophenyl)amino)acrylate?

The CAS number of ethyl 2-(2,6-dichloro-5-fluoronicotinoyl)-3-((2,4-difluorophenyl)amino)acrylate is 100490-99-1.

What are the molecular formula and molecular weight of ethyl 2-(2,6-dichloro-5-fluoronicotinoyl)-3-((2,4-difluorophenyl)amino)acrylate?

ethyl 2-(2,6-dichloro-5-fluoronicotinoyl)-3-((2,4-difluorophenyl)amino)acrylate has molecular formula C17H11Cl2F3N2O3 and molecular weight 419.18200 g/mol.

What are the upstream and downstream products of ethyl 2-(2,6-dichloro-5-fluoronicotinoyl)-3-((2,4-difluorophenyl)amino)acrylate?

For ethyl 2-(2,6-dichloro-5-fluoronicotinoyl)-3-((2,4-difluorophenyl)amino)acrylate, Upstream Products: 2,4-Difluoroaniline, Ethyl 3-(2,6-dichloro-5-fluoropyridin-3-yl)-3-oxopropanoate, Triethyl orthoformate; Downstream Products: 7-Chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid, ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate, ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "ethyl 2-(2,6-dichloro-5-fluoronicotinoyl)-3-((2,4-difluorophenyl)amino)acrylate (CAS 100490-99-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1526567-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.