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4-Chloro-8-methoxyquinoline

Also known as: 4-CHLORO-8-METHOXYQUINOLINE, 4-Chlor-8-methoxychinolin, 4-Chloro-8-Methoxyquinoline, 4-chloro-8-methoxy-quinoline, 4-chloro-8-methoxyquinoline - [C83521], 8-Methoxy-4-chloro quinoline, BB_SC-6159, Quinoline, 4-chloro-8-methoxy-

4-Chloro-8-methoxyquinoline (CAS 16778-21-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C10H8ClNO and a molecular weight of 193.630 g/mol. Key properties include a boiling point of 299.9±20.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 135.2±21.8 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed and H318 — Causes serious eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
16778-21-5
Jingsj CID
J-1525637-8
Molecular Formula
C10H8ClNO
Molecular Weight
193.630 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point299.9±20.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point135.2±21.8 °C
Exact Mass193.029449
PSA22.12000
LogP2.54
Vapor Pressure0.0±0.6 mmHg at 25°C
Refractive Index1.622

GHS Safety & Compliance

Corrosion / IrritantSignal word: Danger
  • H302 — Harmful if swallowed
  • H318 — Causes serious eye damage

Customs & Trade Information

HS Code2933499090
Summary2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 4-Chloro-8-methoxyquinoline?

The CAS number of 4-Chloro-8-methoxyquinoline is 16778-21-5.

What are the molecular formula and molecular weight of 4-Chloro-8-methoxyquinoline?

4-Chloro-8-methoxyquinoline has molecular formula C10H8ClNO and molecular weight 193.630 g/mol.

Is 4-Chloro-8-methoxyquinoline hazardous?

4-Chloro-8-methoxyquinoline has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H318 — Causes serious eye damage.

What are the upstream and downstream products of 4-Chloro-8-methoxyquinoline?

For 4-Chloro-8-methoxyquinoline, Upstream Products: 4-Hydroxy-8-methoxyquinoline, 4-Hydroxy-8-methoxyquinoline-3-carboxylic acid, Ethyl 4-hydroxy-8-methoxyquinoline-3-carboxylate; Downstream Products: 4-Chloro-8-quinolinol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "4-Chloro-8-methoxyquinoline (CAS 16778-21-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1525637-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.