Terbinafine hydrochloride
Also known as: Lamisil, trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine hydrochloride, N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine hydrochloride, (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine monohydrochloride, Terbinafine HCl, 1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-, hydrochloride (1:1)
Terbinafine hydrochloride (CAS 78628-80-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C21H26ClN and a molecular weight of 327.891 g/mol. Key properties include a melting point of 204-208°C, a boiling point of 417.9ºC at 760 mmHg, a density of 1.007g/cm3 and a flash point of 183.7ºC. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 78628-80-5
- Jingsj CID
- J-1516208-0
- Molecular Formula
- C21H26ClN
- Molecular Weight
- 327.891 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 204-208°C |
|---|---|
| Boiling Point | 417.9ºC at 760 mmHg |
| Density | 1.007g/cm3 |
| Flash Point | 183.7ºC |
| Exact Mass | 327.175385 |
| PSA | 3.24000 |
| LogP | 5.67930 |
| Refractive Index | 1.586 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
- H410 — Very toxic to aquatic life with long lasting effects
Activity & Biological Data
| Target | Ki: 30 nM (squalene epoxidase)[1] |
|---|---|
| Additional Information | [1]. Ryder NS, et al. Terbinafine: mode of action and properties of the squalene epoxidase inhibition. Br J Dermatol. 1992 Feb;126 Suppl 39:2-8. [2]. Mieth H, et al. Preclinical evaluation of terbinafine in vivo. Clin Exp Dermatol. 1989 Mar;14(2):104-8. |
Customs & Trade Information
| HS Code | 2921499090 |
|---|---|
| Summary | 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Terbinafine hydrochloride?
The CAS number of Terbinafine hydrochloride is 78628-80-5.
What are the molecular formula and molecular weight of Terbinafine hydrochloride?
Terbinafine hydrochloride has molecular formula C21H26ClN and molecular weight 327.891 g/mol.
Is Terbinafine hydrochloride hazardous?
Terbinafine hydrochloride has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of Terbinafine hydrochloride?
For Terbinafine hydrochloride, Upstream Products: N-Methyl-1-naphthalenemethylamine, 6,6-Dimethyl-1-hepten-4-yn-3-ol, Terbinafine; Downstream Products: Terbinafine.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Terbinafine hydrochloride (CAS 78628-80-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1516208-0 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.