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2,5-Dichloropyrimidine

Also known as: 2,5-Dichloro-1,3-diazine, Pyrimidine, 2,5-dichloro-, 2,5-chloropyrimidine, EOS-60492, Macitentan Impurity 32, T6N CNJ BG EG

2,5-Dichloropyrimidine (CAS 22536-67-0) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C4H2Cl2N2 and a molecular weight of 148.978 g/mol. Key properties include a melting point of 57.0-57.5ºC, a boiling point of 265.3±13.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 139.8±5.4 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed, H318 — Causes serious eye damage and H400 — Very toxic to aquatic life. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
22536-67-0
Jingsj CID
J-1515670-4
Molecular Formula
C4H2Cl2N2
Molecular Weight
148.978 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point57.0-57.5ºC
Boiling Point265.3±13.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Flash Point139.8±5.4 °C
Exact Mass147.959503
PSA25.78000
LogP1.18
Vapor Pressure0.0±0.5 mmHg at 25°C
Refractive Index1.559

GHS Safety & Compliance

Corrosion / Irritant / Environmental HazardSignal word: Danger
  • H302 — Harmful if swallowed
  • H318 — Causes serious eye damage
  • H400 — Very toxic to aquatic life

Customs & Trade Information

HS Code2933599090
Summary2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 2,5-Dichloropyrimidine?

The CAS number of 2,5-Dichloropyrimidine is 22536-67-0.

What are the molecular formula and molecular weight of 2,5-Dichloropyrimidine?

2,5-Dichloropyrimidine has molecular formula C4H2Cl2N2 and molecular weight 148.978 g/mol.

Is 2,5-Dichloropyrimidine hazardous?

2,5-Dichloropyrimidine has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H318 — Causes serious eye damage; H400 — Very toxic to aquatic life.

What are the upstream and downstream products of 2,5-Dichloropyrimidine?

For 2,5-Dichloropyrimidine, Upstream Products: 2,4,5-Trichloropyrimidine, 5-Chloropyrimidin-2(1H)-one, 2-Amino-5-chloropyrimidine; Downstream Products: 5-Chloro-2-methoxypyrimidine, Pyrimidine, 5-Chloro-2-iodopyrimidine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2,5-Dichloropyrimidine (CAS 22536-67-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1515670-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.