Darexaban

Also known as: Darexaban (YM150, Darexaban, Tanexaban, N-(3-Hydroxy-2-(4-(4-methyl-1,4-diazepan-1-yl)benzamido)phenyl)-4-methoxybenzamide, N-[2-Hydroxy-6-(4-methoxybenzamido)phenyl]-4-(4-methyl-1,4-diazepan-1-yl)benzamide, N-[2-hydroxy-6-[(4-methoxybenzoyl)amino]phenyl]-4-(4-methyl-1,4-diazepan-1-yl)benzamide, Tanexaban, UNII-KF322K101S, YM 150), YM-150

Darexaban (CAS 365462-23-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C27H30N4O4 and a molecular weight of 474.55 g/mol. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 365462-23-3
Jingsj CID: J-1514025-7
Molecular Formula: C₂₇H₃₀N₄O₄
Molecular Weight: 474.55 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Exact Mass	474.22700
PSA	94.14000
LogP	4.19620

Activity & Biological Data

Additional Information	[1]. Fukushi Hirayama, et al. Discovery of N-[2-hydroxy-6-(4-methoxybenzamido)phenyl]-4- (4-methyl-1,4-diazepan-1-yl)benzamide (darexaban, YM150) as a potent and orally available factor Xa inhibitor. J Med Chem. 2011 Dec 8;54(23):8051-65. [2]. Seiji Kaku, et al. Darexaban: anticoagulant effects in mice and human plasma in vitro, antithrombotic effects in thrombosis and bleeding models in mice and effects of anti-inhibitor coagulant complex and recombinant factor VIIa. Thromb Res. 2013 May;131(5):450-6. [3]. Milan Remko, et al. Theoretical Study of Molecular Structure and Physicochemical Properties of Novel Factor Xa Inhibitors and Dual Factor Xa and Factor IIa Inhibitors. Molecules. 2016 Feb 4;21(2):185.

Additional Information

[1]. Fukushi Hirayama, et al. Discovery of N-[2-hydroxy-6-(4-methoxybenzamido)phenyl]-4- (4-methyl-1,4-diazepan-1-yl)benzamide (darexaban, YM150) as a potent and orally available factor Xa inhibitor. J Med Chem. 2011 Dec 8;54(23):8051-65. [2]. Seiji Kaku, et al. Darexaban: anticoagulant effects in mice and human plasma in vitro, antithrombotic effects in thrombosis and bleeding models in mice and effects of anti-inhibitor coagulant complex and recombinant factor VIIa. Thromb Res. 2013 May;131(5):450-6. [3]. Milan Remko, et al. Theoretical Study of Molecular Structure and Physicochemical Properties of Novel Factor Xa Inhibitors and Dual Factor Xa and Factor IIa Inhibitors. Molecules. 2016 Feb 4;21(2):185.

Frequently Asked Questions

What is the CAS number of Darexaban?

The CAS number of Darexaban is 365462-23-3.

What are the molecular formula and molecular weight of Darexaban?

Darexaban has molecular formula C27H30N4O4 and molecular weight 474.55 g/mol.

What are the upstream and downstream products of Darexaban?

For Darexaban, Upstream Products: 2-Amino-3-nitrophenol, 4-Methoxybenzoyl chloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Darexaban (CAS 365462-23-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1514025-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.