Ethyl (R)-1-(tert-butoxycarbonyl)-3-piperidinecarboxylate

Also known as: Ethyl (R)-1-Boc-nipecotate, (R)-1-Boc-nipecotic acid ethyl ester, Ethyl (R)-N-Boc-piperidine-3-carboxylate, Ethyl (3R)-1-tert-butoxycarbonyl-3-piperidinecarboxylate, 1-tert-Butyl 3-ethyl (3R)-piperidine-1,3-dicarboxylate, (R)-1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid ethyl ester, Ethyl (R)-1-Boc-3-piperidinecarboxylate, (R)-1,3-Piperidinedicarboxylic acid 1-tert-butyl 3-ethyl ester

Ethyl (R)-1-(tert-butoxycarbonyl)-3-piperidinecarboxylate (CAS 194726-40-4) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C13H23NO4 and a molecular weight of 257.326 g/mol. Key properties include a melting point of 37 °C, a boiling point of 323.9±35.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 149.7±25.9 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 194726-40-4
Jingsj CID: J-1513522-5
Molecular Formula: C₁₃H₂₃NO₄
Molecular Weight: 257.326 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	37 °C
Boiling Point	323.9±35.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	149.7±25.9 °C
Exact Mass	257.162720
PSA	55.84000
LogP	2.09
Vapor Pressure	0.0±0.7 mmHg at 25°C
Refractive Index	1.473

GHS Safety & Compliance

IrritantSignal word: Warning

H302 — Harmful if swallowed
H315 — Causes skin irritation
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation

Frequently Asked Questions

What is the CAS number of Ethyl (R)-1-(tert-butoxycarbonyl)-3-piperidinecarboxylate?

The CAS number of Ethyl (R)-1-(tert-butoxycarbonyl)-3-piperidinecarboxylate is 194726-40-4.

What are the molecular formula and molecular weight of Ethyl (R)-1-(tert-butoxycarbonyl)-3-piperidinecarboxylate?

Ethyl (R)-1-(tert-butoxycarbonyl)-3-piperidinecarboxylate has molecular formula C13H23NO4 and molecular weight 257.326 g/mol.

Is Ethyl (R)-1-(tert-butoxycarbonyl)-3-piperidinecarboxylate hazardous?

Ethyl (R)-1-(tert-butoxycarbonyl)-3-piperidinecarboxylate has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of Ethyl (R)-1-(tert-butoxycarbonyl)-3-piperidinecarboxylate?

For Ethyl (R)-1-(tert-butoxycarbonyl)-3-piperidinecarboxylate, Upstream Products: Di-tert-butyl dicarbonate, Ethyl (R)-nipecotate, Ethyl nicotinate; Downstream Products: tert-Butyl (R)-3-formylpiperidine-1-carboxylate, (R)-Boc-Nipecotic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Ethyl (R)-1-(tert-butoxycarbonyl)-3-piperidinecarboxylate (CAS 194726-40-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1513522-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.