4-Phenyl-5-(trifluoromethyl)thiophene-2-carboxylic acid

Also known as: 4-Phenyl-5-(trifluoromethyl)-2-thiophenecarboxylic acid, 2-Thiophenecarboxylic acid, 4-phenyl-5-(trifluoromethyl)-, 4-Phenyl-5-(trifluoromethyl)-2-thenoic acid, 5-Carboxy-3-phenyl-2-(trifluoromethyl)thiophene, 5-trifluoromethyl-4-phenyl-thiophene-2-carboxylic acid, HMS1449K04, BUTTPARK 82\12-88

4-Phenyl-5-(trifluoromethyl)thiophene-2-carboxylic acid (CAS 208108-76-3) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C12H7F3O2S and a molecular weight of 272.243 g/mol. Key properties include a melting point of 130ºC, a boiling point of 366.5±42.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 175.5±27.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 208108-76-3
Jingsj CID: J-1505959-3
Molecular Formula: C₁₂H₇F₃O₂S
Molecular Weight: 272.243 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	130ºC
Boiling Point	366.5±42.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	175.5±27.9 °C
Exact Mass	272.011871
PSA	65.54000
LogP	5.37
Vapor Pressure	0.0±0.9 mmHg at 25°C
Refractive Index	1.556

Customs & Trade Information

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 4-Phenyl-5-(trifluoromethyl)thiophene-2-carboxylic acid?

The CAS number of 4-Phenyl-5-(trifluoromethyl)thiophene-2-carboxylic acid is 208108-76-3.

What are the molecular formula and molecular weight of 4-Phenyl-5-(trifluoromethyl)thiophene-2-carboxylic acid?

4-Phenyl-5-(trifluoromethyl)thiophene-2-carboxylic acid has molecular formula C12H7F3O2S and molecular weight 272.243 g/mol.

What are the upstream and downstream products of 4-Phenyl-5-(trifluoromethyl)thiophene-2-carboxylic acid?

For 4-Phenyl-5-(trifluoromethyl)thiophene-2-carboxylic acid, Upstream Products: ethyl 4-phenyl-5-(trifluoromethyl)thiophene-2-carboxylate, 1,1,1-Trifluoro-3-phenylacetone; Downstream Products: 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride, 1-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]ethan-1-one, (4-Phenyl-5-(trifluoromethyl)thiophen-2-yl)methanol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "4-Phenyl-5-(trifluoromethyl)thiophene-2-carboxylic acid (CAS 208108-76-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1505959-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.