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Methyl 3-aminothiophene-2-carboxylate

Also known as: 3-Amino-2-thiophenecarboxylic acid methyl ester, 3-Aminothiophene-2-carboxylic acid methyl ester, 3-Amino-2-methoxycarbonylthiophene, Methyl 3-amino-2-thiophenecarboxylate, 3-Amino-2-carbomethoxythiophene, Methyl 3-amino-2-thenoate, 3-Aminothiophen-2-carboxylic acid methyl ester, 2-Thiophenecarboxylic acid, 3-amino-, methyl ester, 2-Methoxycarbonyl-3-aminothiophene

Methyl 3-aminothiophene-2-carboxylate (CAS 22288-78-4) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C6H7NO2S and a molecular weight of 157.190 g/mol. Key properties include a melting point of 62-64 °C(lit.), a boiling point of 334.6±0.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 138.1±22.3 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
22288-78-4
Jingsj CID
J-1498357-4
Molecular Formula
C6H7NO2S
Molecular Weight
157.190 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point62-64 °C(lit.)
Boiling Point334.6±0.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point138.1±22.3 °C
Exact Mass157.019745
PSA80.56000
LogP1.64
Vapor Pressure0.0±0.7 mmHg at 25°C
Refractive Index1.598

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2934999090
Summary2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Methyl 3-aminothiophene-2-carboxylate?

The CAS number of Methyl 3-aminothiophene-2-carboxylate is 22288-78-4.

What are the molecular formula and molecular weight of Methyl 3-aminothiophene-2-carboxylate?

Methyl 3-aminothiophene-2-carboxylate has molecular formula C6H7NO2S and molecular weight 157.190 g/mol.

Is Methyl 3-aminothiophene-2-carboxylate hazardous?

Methyl 3-aminothiophene-2-carboxylate has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Methyl 3-aminothiophene-2-carboxylate?

For Methyl 3-aminothiophene-2-carboxylate, Upstream Products: Methyl 3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylate, Nicotinaldehyde, Methyl 3-oxotetrahydrothiophene-2-carboxylate; Downstream Products: Methyl thiophene-2-carboxylate, Methyl 3-chlorosulfonylthiophene-2-carboxylate, 3-Fluoro-2-thiophenecarboxylic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Methyl 3-aminothiophene-2-carboxylate (CAS 22288-78-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1498357-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.