Nefazodone

Also known as: Serzone, BMY-13754, MJ-13754-1, Nefazodone base, 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazol-3-one, 3H-1,2,4-triazol-3-one, 2,4-dihydro-2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-4-(2-phenoxyethyl)-, UNII-59H4FCV1TF, Nefazodona, Nefazodonum, Dutonin

Nefazodone (CAS 83366-66-9) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C25H32ClN5O2 and a molecular weight of 470.00700 g/mol. Key property: a melting point of 180-182°C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 83366-66-9
Jingsj CID: J-14967-7
Molecular Formula: C₂₅H₃₂ClN₅O₂
Molecular Weight: 470.00700 g/mol
Category: Ketones
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	180-182°C
Exact Mass	469.22400
PSA	55.53000
LogP	3.55480
Additional Property	DMSO: ~11 mg/mL at 60 °C

Activity & Biological Data

Target	5-HT receptor, Noradrenaline, CYP3A4[1]

Frequently Asked Questions

What is the CAS number of Nefazodone?

The CAS number of Nefazodone is 83366-66-9.

What are the molecular formula and molecular weight of Nefazodone?

Nefazodone has molecular formula C25H32ClN5O2 and molecular weight 470.00700 g/mol.

What are the upstream and downstream products of Nefazodone?

For Nefazodone, Upstream Products: 5-Ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one, 1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Nefazodone (CAS 83366-66-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-14967-7 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.