2-Amino-4-(trifluoromethyl)pyrimidine
Also known as: 4-(Trifluoromethyl)pyrimidin-2-amine, 2-Pyrimidinamine, 4-(trifluoromethyl)-, 4-(Trifluoromethyl)-2-pyrimidinamine, AKOS B024896, ART-CHEM-BB B024896, MFCD00828624
2-Amino-4-(trifluoromethyl)pyrimidine (CAS 16075-42-6) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C5H4F3N3 and a molecular weight of 163.101 g/mol. Key properties include a melting point of 175-177ºC, a boiling point of 260.7±50.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 111.5±30.1 °C. It is classified under GHS with signal word Danger and hazard statements H300, H319 — Causes serious eye irritation and H334 — May cause allergy or asthma symptoms if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 16075-42-6
- Jingsj CID
- J-1494256-4
- Molecular Formula
- C5H4F3N3
- Molecular Weight
- 163.101 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 175-177ºC |
|---|---|
| Boiling Point | 260.7±50.0 °C at 760 mmHg |
| Density | 1.5±0.1 g/cm3 |
| Flash Point | 111.5±30.1 °C |
| Exact Mass | 163.035736 |
| PSA | 51.80000 |
| LogP | 0.75 |
| Vapor Pressure | 0.0±0.5 mmHg at 25°C |
| Refractive Index | 1.479 |
GHS Safety & Compliance
- H300
- H319 — Causes serious eye irritation
- H334 — May cause allergy or asthma symptoms if inhaled
- H400 — Very toxic to aquatic life
Customs & Trade Information
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of 2-Amino-4-(trifluoromethyl)pyrimidine?
The CAS number of 2-Amino-4-(trifluoromethyl)pyrimidine is 16075-42-6.
What are the molecular formula and molecular weight of 2-Amino-4-(trifluoromethyl)pyrimidine?
2-Amino-4-(trifluoromethyl)pyrimidine has molecular formula C5H4F3N3 and molecular weight 163.101 g/mol.
Is 2-Amino-4-(trifluoromethyl)pyrimidine hazardous?
2-Amino-4-(trifluoromethyl)pyrimidine has GHS signal word Danger and hazard statements H300; H319 — Causes serious eye irritation; H334 — May cause allergy or asthma symptoms if inhaled.
What are the upstream and downstream products of 2-Amino-4-(trifluoromethyl)pyrimidine?
For 2-Amino-4-(trifluoromethyl)pyrimidine, Upstream Products: 5-bromo-4-(trifluoromethyl)pyrimidin-2-amine, Bis(pinacolato)diboron, (E)-4-ethoxy-1,1,1-trifluorobut-3-en-2-one; Downstream Products: (2-Amino-4-(trifluoromethyl)pyrimidin-5-yl)boronic acid, 3-Bromo-7-(trifluoromethyl)imidazo[1,2-a]pyrimidine, 2-Amino-4-(trifluoromethyl)pyrimidine-5-boronic acid pinacol ester.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "2-Amino-4-(trifluoromethyl)pyrimidine (CAS 16075-42-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1494256-4 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.