Sivelestat
Also known as: ONO-5046, LY544349, EI546, N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine, 2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetic acid, o-(p-Hydroxybenzenesulfonamido)hippuric Acid Pivalate (Ester), Elastase Inhibitor IV
Sivelestat (CAS 127373-66-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H22N2O7S and a molecular weight of 434.463 g/mol. Key property: a density of 1.4±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 127373-66-4
- Jingsj CID
- J-1492530-5
- Molecular Formula
- C20H22N2O7S
- Molecular Weight
- 434.463 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Exact Mass | 434.114777 |
| PSA | 147.25000 |
| LogP | 2.96 |
| Refractive Index | 1.598 |
| Storage Conditions | -20℃ |
Activity & Biological Data
| Additional Information | [1]. Kawabata K, et al. ONO-5046, a novel inhibitor of human neutrophil elastase. Biochem Biophys Res Commun. 1991 Jun 14;177(2):814-20. [2]. Imokawa S, et al. Acute respiratory failure due to pneumocystis pneumonia successfully treated with combined use of sivelestat sodium hydrate. Nihon Kokyuki Gakkai Zasshi. 2008 Jun;46(6):461-5. |
|---|
Customs & Trade Information
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
Frequently Asked Questions
What is the CAS number of Sivelestat?
The CAS number of Sivelestat is 127373-66-4.
What are the molecular formula and molecular weight of Sivelestat?
Sivelestat has molecular formula C20H22N2O7S and molecular weight 434.463 g/mol.
What are the upstream and downstream products of Sivelestat?
For Sivelestat, Upstream Products: 2-Aminohippuric acid, 4-(Chlorosulfonyl)phenyl pivalate, Pivaloyl chloride.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Sivelestat (CAS 127373-66-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1492530-5 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.