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N-[(Benzyloxy)carbonyl]-L-leucine

Also known as: Z-Leu-OH, Cbz-L-Leu-OH, N-Benzyloxycarbonyl-L-leucine, N-Carbobenzyloxy-L-leucine, N-Carbobenzoxy-L-leucine, N-Cbz-L-leucine, Benzyloxycarbonyl-L-leucine, Benzyloxycarbonylleucine, Carbobenzoxyleucine, (S)-2-(((Benzyloxy)carbonyl)amino)-4-methylpentanoic acid

N-[(Benzyloxy)carbonyl]-L-leucine (CAS 2018-66-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C14H19NO4 and a molecular weight of 265.305 g/mol. Key properties include a boiling point of 442.8±38.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 221.6±26.8 °C. It is classified under GHS with signal word Warning and hazard statements H226 — Flammable liquid and vapour and H351 — Suspected of causing cancer. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
2018-66-8
Jingsj CID
J-14374-8
Molecular Formula
C14H19NO4
Molecular Weight
265.305 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point442.8±38.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point221.6±26.8 °C
Exact Mass265.131409
PSA75.63000
LogP3.12
Vapor Pressure0.0±1.1 mmHg at 25°C
Refractive Index1.528

GHS Safety & Compliance

Flammable / Health HazardSignal word: Warning
  • H226 — Flammable liquid and vapour
  • H351 — Suspected of causing cancer

Activity & Biological Data

Additional Information[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Customs & Trade Information

HS Code2924299090
Summary2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of N-[(Benzyloxy)carbonyl]-L-leucine?

The CAS number of N-[(Benzyloxy)carbonyl]-L-leucine is 2018-66-8.

What are the molecular formula and molecular weight of N-[(Benzyloxy)carbonyl]-L-leucine?

N-[(Benzyloxy)carbonyl]-L-leucine has molecular formula C14H19NO4 and molecular weight 265.305 g/mol.

Is N-[(Benzyloxy)carbonyl]-L-leucine hazardous?

N-[(Benzyloxy)carbonyl]-L-leucine has GHS signal word Warning and hazard statements H226 — Flammable liquid and vapour; H351 — Suspected of causing cancer.

What are the upstream and downstream products of N-[(Benzyloxy)carbonyl]-L-leucine?

For N-[(Benzyloxy)carbonyl]-L-leucine, Upstream Products: L-Leucine, N-Cbz-L-leucine methyl ester, Z-Leu-ONp; Downstream Products: N-Cbz-N-methyl-L-leucine, Z-Leu-OSu, (S)-N-Cbz-Leucinenitrile.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "N-[(Benzyloxy)carbonyl]-L-leucine (CAS 2018-66-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-14374-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.