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2-[(Difluoromethyl)sulfonyl]pyridine

Also known as: 2-(Difluoromethanesulfonyl)pyridine, 2-(difluoromethylsulfonyl)pyridine, 2-PySO2CF2H, Difluoromethyl 2-Pyridyl Sulfone, Hu Reagent, Pyridine, 2-[(difluoromethyl)sulfonyl]-

2-[(Difluoromethyl)sulfonyl]pyridine (CAS 1219454-89-3) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C6H5F2NO2S and a molecular weight of 193.171 g/mol. Key properties include a boiling point of 324.4±42.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 150.0±27.9 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
1219454-89-3
Jingsj CID
J-1403906-6
Molecular Formula
C6H5F2NO2S
Molecular Weight
193.171 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point324.4±42.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point150.0±27.9 °C
Exact Mass193.000900
PSA55.41000
LogP0.38
Vapor Pressure0.0±0.7 mmHg at 25°C
Refractive Index1.475

GHS Safety & Compliance

Acute ToxicitySignal word: Danger
  • H301 — Toxic if swallowed
  • H319 — Causes serious eye irritation

Customs & Trade Information

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 2-[(Difluoromethyl)sulfonyl]pyridine?

The CAS number of 2-[(Difluoromethyl)sulfonyl]pyridine is 1219454-89-3.

What are the molecular formula and molecular weight of 2-[(Difluoromethyl)sulfonyl]pyridine?

2-[(Difluoromethyl)sulfonyl]pyridine has molecular formula C6H5F2NO2S and molecular weight 193.171 g/mol.

Is 2-[(Difluoromethyl)sulfonyl]pyridine hazardous?

2-[(Difluoromethyl)sulfonyl]pyridine has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H319 — Causes serious eye irritation.

What are the upstream and downstream products of 2-[(Difluoromethyl)sulfonyl]pyridine?

For 2-[(Difluoromethyl)sulfonyl]pyridine, Upstream Products: 2-Mercaptopyridine; Downstream Products: 2(1H)-Pyridone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2-[(Difluoromethyl)sulfonyl]pyridine (CAS 1219454-89-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1403906-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.