N-Benzyloxycarbonyl-L-proline tert-butyl ester

Also known as: Z-Pro-OtBu, Z-L-Pro-OtBu, Cbz-Pro-OtBu, N-Cbz-L-proline tert-butyl ester, N-Carbobenzoxy-L-proline tert-butyl ester, 1-Benzyl 2-tert-butyl (2S)-pyrrolidine-1,2-dicarboxylate, 1-Benzyl 2-(2-methyl-2-propanyl) (2S)-1,2-pyrrolidinedicarboxylate, (S)-1-Benzyl 2-tert-butyl pyrrolidine-1,2-dicarboxylate, N-ALPHA-BENZYLOXYCARBONYL-L-PROLINE-TERT-BUTYL ESTER, N-ALPHA-CARBOBENZOXY-L-PROLINE ALPHA-T-BUTYL ESTER, N-Carbobenzoxy-L-proline tert-Butyl Ester, Z-L-proline t-butyl ester, MFCD00051777, EINECS 240-911-2

N-Benzyloxycarbonyl-L-proline tert-butyl ester (CAS 16881-39-3) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C17H23NO4 and a molecular weight of 305.369 g/mol. Key properties include a melting point of 45ºC, a boiling point of 404.8±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 198.6±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 16881-39-3
Jingsj CID: J-1378461-7
Molecular Formula: C₁₇H₂₃NO₄
Molecular Weight: 305.369 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	45ºC
Boiling Point	404.8±45.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	198.6±28.7 °C
Exact Mass	305.162720
PSA	55.84000
LogP	2.87
Vapor Pressure	0.0±0.9 mmHg at 25°C
Refractive Index	1.533
Storage Conditions	-15°C

Activity & Biological Data

Additional Information	[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of N-Benzyloxycarbonyl-L-proline tert-butyl ester?

The CAS number of N-Benzyloxycarbonyl-L-proline tert-butyl ester is 16881-39-3.

What are the molecular formula and molecular weight of N-Benzyloxycarbonyl-L-proline tert-butyl ester?

N-Benzyloxycarbonyl-L-proline tert-butyl ester has molecular formula C17H23NO4 and molecular weight 305.369 g/mol.

What are the upstream and downstream products of N-Benzyloxycarbonyl-L-proline tert-butyl ester?

For N-Benzyloxycarbonyl-L-proline tert-butyl ester, Upstream Products: N-Benzyloxycarbonyl-L-proline, tert-Butanol, Di-tert-butyl dicarbonate; Downstream Products: tert-Butyl L-prolinate, N-Benzyloxycarbonyl-L-proline.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "N-Benzyloxycarbonyl-L-proline tert-butyl ester (CAS 16881-39-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1378461-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.