Gossypol
Also known as: (+/-)-gossypol, (-)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)[2,2'-binaphthalene]-8,8'-dicarboxaldehyde, (rac)-2,2'-bis(8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene), 1,1',6,6',7,7'-HEXAHYDROXY-3,3'-DIMETHYL-5,5'-BIS(1-METHYLETHYL)-[2,2'-BINAPHTHALENE]-8,8'-DICARBOXALDEHYDE, 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)[2,2'-binaphthalene]-8,8'-dicarboxaldehyde, 1,1',6,6',7,7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-2,2'-binaphthalen-8,8'-dicarbaldehyd, 1,1',6,6',7,7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-2,2'-binaphthalene-8,8'-dicarbaldehyde, 1,1',6,6',7,7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl[2,2'-binaphthalene]-8,8'-dicarboxaldehyde, 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-2,2'-binaphthalene-8,8'-dicarbaldehyde, 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-di(propan-2-yl)-2,2'-binaphthalene-8,8'-dicarbaldehyde, 1,1',6,6',7,7'-hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-(2,2'-binaphthalene)-8,8'-dicarboxaldehyde, 2,2'-BIS[8-FORMYL-1,6,7-TRIHYDROXY-5-ISOPROPYL-3-METHYLNAPHTHALENE], 2,2'-BIS[8-FORMYL-1,6,7-TRIHYDROXY-5-ISOPROPYL-3-METHYLNAPTHALENE], 2,2'-BI[8-FORMYL-1,6,7-TRIHYDROXY-5-ISOPROPYL-3-METHYLNAPHTHALENE], 2,2'-Bis[1,6,7-trihydroxy-3-methyl-5-isopropyl-8-aldehydonaphthalene], 2,2'-bis[8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene], GOSSYPOL, GOSSYPOL(P), Gossypol from cotton seeds,2,2′-bis(8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene), MFCD00017352
Gossypol (CAS 303-45-7) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C30H30O8 and a molecular weight of 518.554 g/mol. Key properties include a melting point of 181-183ºC, a boiling point of 707.9±55.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 395.9±28.0 °C. It is classified under GHS with signal word Warning and hazard statements H351 — Suspected of causing cancer. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 303-45-7
- Jingsj CID
- J-1338016-2
- Molecular Formula
- C30H30O8
- Molecular Weight
- 518.554 g/mol
- Category
- Alcohols
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 181-183ºC |
|---|---|
| Boiling Point | 707.9±55.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 395.9±28.0 °C |
| Exact Mass | 518.194092 |
| PSA | 155.52000 |
| LogP | 6.16 |
| Vapor Pressure | 0.0±2.3 mmHg at 25°C |
| Refractive Index | 1.742 |
GHS Safety & Compliance
- H351 — Suspected of causing cancer
Activity & Biological Data
| Target | Bcl-xL:0.5-0.6 μM (Ki) Bcl-2:0.2-0.3 mM (Ki) |
|---|---|
| Additional Information | [1]. Oliver CL, et al. In vitro effects of the BH3 mimetic, (-)-Gossypol, on head and neck squamous cell carcinoma cells. Clin Cancer Res. 2004 Nov 15;10(22):7757-63. |
Frequently Asked Questions
What is the CAS number of Gossypol?
The CAS number of Gossypol is 303-45-7.
What are the molecular formula and molecular weight of Gossypol?
Gossypol has molecular formula C30H30O8 and molecular weight 518.554 g/mol.
Is Gossypol hazardous?
Gossypol has GHS signal word Warning and hazard statements H351 — Suspected of causing cancer.
What are the upstream and downstream products of Gossypol?
For Gossypol, Upstream Products: 2-Hydroxy-6-isopropyl-3-methylbenzaldehyde, Carvacrol; Downstream Products: Formic Acid, acetic acid, Isobutyric acid.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Gossypol (CAS 303-45-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1338016-2 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.