Celecoxib
Also known as: Celebrex, Celebra, 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide, 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide, YM 177, Solexa, CJ-016377, CP-598107, PF-00345549, PHA-00846533, Celocoxib
Celecoxib (CAS 169590-42-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C17H14F3N3O2S and a molecular weight of 381.372 g/mol. Key properties include a melting point of 157-159ºC, a boiling point of 529.0±60.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 273.7±32.9 °C. GHS signal word: Danger. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 169590-42-5
- Jingsj CID
- J-1324814-1
- Molecular Formula
- C17H14F3N3O2S
- Molecular Weight
- 381.372 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 157-159ºC |
|---|---|
| Boiling Point | 529.0±60.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 273.7±32.9 °C |
| Exact Mass | 381.075867 |
| PSA | 86.36000 |
| LogP | 4.21 |
| Vapor Pressure | 0.0±1.4 mmHg at 25°C |
| Refractive Index | 1.606 |
| Storage Conditions | Store at RT |
GHS Safety & Compliance
Activity & Biological Data
| Target | COX-2:40 nM (IC50) COX-1:15 μM (IC50) |
|---|---|
| Additional Information | [1]. Penning TD, et al. Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib). J Med Chem. 1997 [2]. Liu DB, et al. Celecoxib induces apoptosis and cell-cycle arrest in nasopharyngeal carcinoma cell lines via inhibition of STAT3 phosphorylation. Acta Pharmacol Sin. 2012 May;33(5):682-90. [3]. Suri A, et al. The effect of celecoxib on tumor growth in ovarian cancer cells and a genetically engineered mouse model of serous ovarian cancer. Oncotarget. 2016 Apr 8. [4]. Hou XL, et al. Combination of fasudil and celecoxib promotes the recovery of injured spinal cord in rats better than celecoxib or fasudil alone. Neural Regen Res. 2015 Nov;10(11):1836-40. [5]. Liu C, et al. Celecoxib alleviates nonalcoholic fatty liver disease by restoring autophagic flux. Sci Rep. 2018 Mar 7;8(1):4108. |
Customs & Trade Information
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
Frequently Asked Questions
What is the CAS number of Celecoxib?
The CAS number of Celecoxib is 169590-42-5.
What are the molecular formula and molecular weight of Celecoxib?
Celecoxib has molecular formula C17H14F3N3O2S and molecular weight 381.372 g/mol.
Is Celecoxib hazardous?
Celecoxib has GHS signal word Danger.
What are the upstream and downstream products of Celecoxib?
For Celecoxib, Upstream Products: 4,4,4-Trifluoro-1-(4-methylphenyl)-1,3-butanedione, 4-Hydrazinobenzene-1-sulfonamide hydrochloride, Ethyl trifluoroacetate; Downstream Products: Hydroxymethyl Celecoxib.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Celecoxib (CAS 169590-42-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1324814-1 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.