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Perphenazine

Also known as: Trilafon, Chlorperphenazine, Fentazin, Decentan, Phenazine, Trilifan, PZC, 1-(2-Hydroxyethyl)-4-(3-(2-chloro-10-phenothiazinyl)propyl)piperazine, 2-Chloro-10-[3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl]phenothiazine, 4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol

Perphenazine (CAS 58-39-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C21H26ClN3OS and a molecular weight of 403.97900 g/mol. Key properties include a melting point of 35339ºC, a boiling point of 580.4±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 304.8±30.1 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed and H317 — May cause an allergic skin reaction. No supplier offers are currently listed; request a quote. Record last updated Nov 4, 2026.

CAS No.
58-39-9
Jingsj CID
J-1321099-6
Molecular Formula
C21H26ClN3OS
Molecular Weight
403.97900 g/mol
Category
Organic Compounds
Last updated
11/4/2026

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Physicochemical Properties

Melting Point35339ºC
Boiling Point580.4±50.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point304.8±30.1 °C
Exact Mass403.148499
PSA55.25000
LogP4.34
Vapor Pressure0.0±1.7 mmHg at 25°C
Refractive Index1.627

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed
  • H317 — May cause an allergic skin reaction

Activity & Biological Data

Target5-HT2A Receptor:5.6 nM (Ki) H1 receptor:8 nM (Ki) α1A adrenergic receptor:10 nM (Ki) D2 receptor:0.765 nM (Ki) D3 receptor:0.13 nM (Ki) D2L receptor:3.4 nM (Ki)
Additional Information[1]. Richtand NM, et al. Dopamine and serotonin receptor binding and antipsychotic efficacy. Neuropsychopharmacology. 2007 Aug;32(8):1715-26.

Customs & Trade Information

HS Code2934999090
Summary2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Perphenazine?

The CAS number of Perphenazine is 58-39-9.

What are the molecular formula and molecular weight of Perphenazine?

Perphenazine has molecular formula C21H26ClN3OS and molecular weight 403.97900 g/mol.

Is Perphenazine hazardous?

Perphenazine has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H317 — May cause an allergic skin reaction.

What are the upstream and downstream products of Perphenazine?

For Perphenazine, Upstream Products: 2-Bromoethanol, 2-Chlorophenothiazine, 2-chloro-10-(3-chloropropyl)-10H-phenothiazine; Downstream Products: Dihydrouracil.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Perphenazine (CAS 58-39-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1321099-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.