Clopamide

Also known as: 4-Chloro-N-(cis-2,6-dimethylpiperidino)-3-sulfamoylbenzamide, Brinaldix, Adurix, Aquex, DT-327, 4-Chloro-N-(2,6-dimethyl-1-piperidinyl)-3-sulfamoylbenzamide, 4-Chloro-N-(2,6-dimethylpiperidino)-3-sulfamoylbenzamide, 4-Chloro-N-[(2R,6S)-2,6-dimethyl-1-piperidinyl]-3-sulfamoylbenzamide, 3-(Aminosulfonyl)-4-chloro-N-(2,6-dimethyl-1-piperidinyl)benzamide

Clopamide (CAS 636-54-4) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C14H20ClN3O3S and a molecular weight of 345.845 g/mol. Key properties include a melting point of 244-246ºC and a density of 1.4±0.1 g/cm3. It is classified under GHS with signal word Danger and hazard statements H317 — May cause an allergic skin reaction and H334 — May cause allergy or asthma symptoms if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 636-54-4
Jingsj CID: J-1312384-2
Molecular Formula: C₁₄H₂₀ClN₃O₃S
Molecular Weight: 345.845 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	244-246ºC
Density	1.4±0.1 g/cm3
Exact Mass	345.091400
PSA	100.88000
LogP	1.59
Refractive Index	1.613
Storage Conditions	2-8°C

GHS Safety & Compliance

Health HazardSignal word: Danger

H317 — May cause an allergic skin reaction
H334 — May cause allergy or asthma symptoms if inhaled

Activity & Biological Data

Additional Information	[1]. J J McNeil, et al. Clopamide: plasma concentrations and diuretic effect in humans. Clin Pharmacol Ther. 1987 Sep;42(3):299-304. [2]. Yoshiteru Noutoshi, et al. Diuretics prime plant immunity in Arabidopsis thaliana. PLoS One. 2012;7(10):e48443. [3]. B Odlind, et al. Renal tubular secretion and effects of chlorothiazide, hydrochlorothiazide and clopamide: a study in the avian kidney. Acta Pharmacol Toxicol (Copenh). 1982 Sep;51(3):187-97. [4]. E Müller-Schweinitzer, et al. Interaction of cyclosporine-A with the renin-angiotensin system in canine veins. Naunyn Schmiedebergs Arch Pharmacol. 1989 Aug;340(2):252-7.

Additional Information

[1]. J J McNeil, et al. Clopamide: plasma concentrations and diuretic effect in humans. Clin Pharmacol Ther. 1987 Sep;42(3):299-304. [2]. Yoshiteru Noutoshi, et al. Diuretics prime plant immunity in Arabidopsis thaliana. PLoS One. 2012;7(10):e48443. [3]. B Odlind, et al. Renal tubular secretion and effects of chlorothiazide, hydrochlorothiazide and clopamide: a study in the avian kidney. Acta Pharmacol Toxicol (Copenh). 1982 Sep;51(3):187-97. [4]. E Müller-Schweinitzer, et al. Interaction of cyclosporine-A with the renin-angiotensin system in canine veins. Naunyn Schmiedebergs Arch Pharmacol. 1989 Aug;340(2):252-7.

Customs & Trade Information

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Frequently Asked Questions

What is the CAS number of Clopamide?

The CAS number of Clopamide is 636-54-4.

What are the molecular formula and molecular weight of Clopamide?

Clopamide has molecular formula C14H20ClN3O3S and molecular weight 345.845 g/mol.

Is Clopamide hazardous?

Clopamide has GHS signal word Danger and hazard statements H317 — May cause an allergic skin reaction; H334 — May cause allergy or asthma symptoms if inhaled.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Clopamide (CAS 636-54-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1312384-2 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.