5-Chloro-2-nitroanisole

Also known as: 2-nitro-5-chloroanisole, 4-chloro-2-methoxy-1-nitrobenzene, 4-chloro-2-methoxynitrobenzene, 4-chloro-3-methoxy-1-nitrobenzene, 5-chloro-2-nitrophenyl methyl ether, 5-chloro-2-nitro-1-methoxybenzene, 2-methoxy-4-chloronitrobenzene, NSC 60112

5-Chloro-2-nitroanisole (CAS 6627-53-8) is a compound in the Ethers category listed in the Jingsj chemical database. It has the molecular formula C7H6ClNO3 and a molecular weight of 187.580 g/mol. Key properties include a melting point of 70-72 °C(lit.), a boiling point of 289.1±20.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 128.7±21.8 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 6627-53-8
Jingsj CID: J-1305128-0
Molecular Formula: C₇H₆ClNO₃
Molecular Weight: 187.580 g/mol
Category: Ethers
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	70-72 °C(lit.)
Boiling Point	289.1±20.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	128.7±21.8 °C
Exact Mass	187.003616
PSA	55.05000
LogP	2.61
Vapor Pressure	0.0±0.6 mmHg at 25°C
Refractive Index	1.560

GHS Safety & Compliance

IrritantSignal word: Warning

H315 — Causes skin irritation
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation

Customs & Trade Information

HS Code	2909309090
Summary	2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 5-Chloro-2-nitroanisole?

The CAS number of 5-Chloro-2-nitroanisole is 6627-53-8.

What are the molecular formula and molecular weight of 5-Chloro-2-nitroanisole?

5-Chloro-2-nitroanisole has molecular formula C7H6ClNO3 and molecular weight 187.580 g/mol.

Is 5-Chloro-2-nitroanisole hazardous?

5-Chloro-2-nitroanisole has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of 5-Chloro-2-nitroanisole?

For 5-Chloro-2-nitroanisole, Upstream Products: 5-Chloro-2-nitrophenol, iodomethane, 1-Chloro-3,4-dinitrobenzene; Downstream Products: 2,4-Dimethoxy-1-nitrobenzene, 5-Methoxy-2-nitrophenol, 7-Methoxyindole.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "5-Chloro-2-nitroanisole (CAS 6627-53-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1305128-0 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.