1-Boc-piperazine
Also known as: tert-Butyl piperazine-1-carboxylate, N-Boc-piperazine, 1-(tert-Butoxycarbonyl)piperazine, 1-Piperazinecarboxylic acid tert-butyl ester, PIBOC, BOC-piperazine
1-Boc-piperazine (CAS 57260-71-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C9H18N2O2 and a molecular weight of 186.251 g/mol. Key properties include a melting point of 47-49ºC, a boiling point of 258.0±15.0 °C at 760 mmHg, a density of 1.0±0.1 g/cm3 and a flash point of 109.8±20.4 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 57260-71-6
- Jingsj CID
- J-13017-6
- Molecular Formula
- C9H18N2O2
- Molecular Weight
- 186.251 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 47-49ºC |
|---|---|
| Boiling Point | 258.0±15.0 °C at 760 mmHg |
| Density | 1.0±0.1 g/cm3 |
| Flash Point | 109.8±20.4 °C |
| Exact Mass | 186.136826 |
| PSA | 41.57000 |
| LogP | 0.55 |
| Vapor Pressure | 0.0±0.5 mmHg at 25°C |
| Refractive Index | 1.467 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | Alkyl/ether |
|---|---|
| Additional Information | [1]. Binbin Cheng, et al. Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1. Eur J Med Chem. 2020;199:112377. |
Customs & Trade Information
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of 1-Boc-piperazine?
The CAS number of 1-Boc-piperazine is 57260-71-6.
What are the molecular formula and molecular weight of 1-Boc-piperazine?
1-Boc-piperazine has molecular formula C9H18N2O2 and molecular weight 186.251 g/mol.
Is 1-Boc-piperazine hazardous?
1-Boc-piperazine has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of 1-Boc-piperazine?
For 1-Boc-piperazine, Upstream Products: Piperazine, Di-tert-butyl dicarbonate, tert-Butyl 4-(methylsulfonyl)piperazine-1-carboxylate; Downstream Products: 4-(4-Boc-1-piperazinyl)-5-bromo-7H-pyrrolo[2,3-d]pyrimidine, tert-butyl 4-(3-bromophenyl)piperazine-1-carboxylate, 1-(4-Chlorophenyl)piperazine.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "1-Boc-piperazine (CAS 57260-71-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-13017-6 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.