Fulvestrant

Also known as: Faslodex, ICI 182,780, ZD 9238, (7R,8R,9S,13S,14S,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol, Estra-1,3,5(10)-triene-3,17-diol, 7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-, (17β)-, MFCD00903953

Fulvestrant (CAS 129453-61-8) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C32H47F5O3S and a molecular weight of 606.771 g/mol. Key properties include a melting point of 104-106°C, a boiling point of 674.8±55.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 361.9±31.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 129453-61-8
Jingsj CID: J-12286-9
Molecular Formula: C₃₂H₄₇F₅O₃S
Molecular Weight: 606.771 g/mol
Category: Organohalogen Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	104-106°C
Boiling Point	674.8±55.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	361.9±31.5 °C
Exact Mass	606.316589
PSA	76.74000
LogP	7.92
Vapor Pressure	0.0±2.2 mmHg at 25°C
Refractive Index	1.522

Activity & Biological Data

Target	IC50: 9.4 nM (Estrogen Receptor)[1]
Additional Information	[1]. Wakeling AE, et al. A potent specific pure antiestrogen with clinical potential. Cancer Res. 1991 Aug 1;51(15):3867-73. [2]. Osborne CK, et al. Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action. Br J Cancer. 2004 Mar;90 Suppl 1:S2-6. [3]. Garner F, et al. RAD1901: a novel, orally bioavailable selective estrogen receptor degrader that demonstrates antitumor activity in breast cancer xenograft models. Anticancer Drugs. 2015 Oct;26(9):948-56

Target

IC50: 9.4 nM (Estrogen Receptor)[1]

Additional Information

[1]. Wakeling AE, et al. A potent specific pure antiestrogen with clinical potential. Cancer Res. 1991 Aug 1;51(15):3867-73. [2]. Osborne CK, et al. Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action. Br J Cancer. 2004 Mar;90 Suppl 1:S2-6. [3]. Garner F, et al. RAD1901: a novel, orally bioavailable selective estrogen receptor degrader that demonstrates antitumor activity in breast cancer xenograft models. Anticancer Drugs. 2015 Oct;26(9):948-56

Customs & Trade Information

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Fulvestrant?

The CAS number of Fulvestrant is 129453-61-8.

What are the molecular formula and molecular weight of Fulvestrant?

Fulvestrant has molecular formula C32H47F5O3S and molecular weight 606.771 g/mol.

What are the upstream and downstream products of Fulvestrant?

For Fulvestrant, Upstream Products: (7α,17β)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)thio]nonyl]estra-1,3,5(10)-triene-3,17-diol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Fulvestrant (CAS 129453-61-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-12286-9 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.