[(3S,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methyl 4-methylbenzenesulfonate

(3S,5R)-甲苯-4-磺酸-5-(2,4-二氟苯基)-5-(1H-1,2,4-三唑-1-基)甲基四氢呋喃-3-基甲基酯

Also known as: (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester, Posaconazole Intermediate 12, ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate, 4-methylbenzenesulfonic acid [(3S,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)tetrahydrofuran-3-yl]methyl ester, Posaconazole main ring (tosylate)

[(3S,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methyl 4-methylbenzenesulfonate (CAS 149809-43-8) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C21H21F2N3O4S and a molecular weight of 449.471 g/mol. It is also known as (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester, Posaconazole Intermediate 12 and ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate. Key properties include a melting point of 100-102°C, a boiling point of 600.3±65.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 316.8±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.

149809-43-8

Jingsj CID

J-1162341-8

Molecular Formula

C₂₁H₂₁F₂N₃O₄S

Chinese Name

(3S,5R)-甲苯-4-磺酸-5-(2,4-二氟苯基)-5-(1H-1,2,4-三唑-1-基)甲基四氢呋喃-3-基甲基酯

Molecular Weight

449.471 g/mol

Category

Pharma Intermediates

Last updated

8/21/2026