2-Hydroxy-6-(thiophen-2-yl)-4-(trifluoromethyl)nicotinonitrile

Also known as: 2-Oxo-6-(thiophen-2-yl)-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile, 3-Cyano-6-(2-thienyl)-4-(trifluoromethyl)-2(1H)-pyridone, 2-Hydroxy-6-(thien-2-yl)-4-(trifluoromethyl)pyridine-3-carbonitrile, 3-Pyridinecarbonitrile, 1,2-dihydro-2-oxo-6-(2-thienyl)-4-(trifluoromethyl)-

2-Hydroxy-6-(thiophen-2-yl)-4-(trifluoromethyl)nicotinonitrile (CAS 3335-45-3) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C11H5F3N2OS and a molecular weight of 270.23000 g/mol. Key properties include a melting point of 278ºC, a boiling point of 390.2ºC at 760mmHg, a density of 1.52g/cm3 and a flash point of 189.8ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 3335-45-3
Jingsj CID: J-1142044-3
Molecular Formula: C₁₁H₅F₃N₂OS
Molecular Weight: 270.23000 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	278ºC
Boiling Point	390.2ºC at 760mmHg
Density	1.52g/cm3
Flash Point	189.8ºC
Exact Mass	270.00700
PSA	85.15000
LogP	3.40618

Customs & Trade Information

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 2-Hydroxy-6-(thiophen-2-yl)-4-(trifluoromethyl)nicotinonitrile?

The CAS number of 2-Hydroxy-6-(thiophen-2-yl)-4-(trifluoromethyl)nicotinonitrile is 3335-45-3.

What are the molecular formula and molecular weight of 2-Hydroxy-6-(thiophen-2-yl)-4-(trifluoromethyl)nicotinonitrile?

2-Hydroxy-6-(thiophen-2-yl)-4-(trifluoromethyl)nicotinonitrile has molecular formula C11H5F3N2OS and molecular weight 270.23000 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "2-Hydroxy-6-(thiophen-2-yl)-4-(trifluoromethyl)nicotinonitrile (CAS 3335-45-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1142044-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.