2-Chloro-5-(chloromethyl)thiazole

Also known as: 2-Chloro-5-chloromethylthiazole, 2-Chloro-5-(chloromethyl)-1,3-thiazole, Thiazole, 2-chloro-5-(chloromethyl)-, 2-Chloro-5-(chlormethyl)thiazole

2-Chloro-5-(chloromethyl)thiazole (CAS 105827-91-6) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C4H3Cl2NS and a molecular weight of 168.044 g/mol. Key properties include a melting point of 31ºC, a boiling point of 268.6±32.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 116.3±25.1 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed, H311 — Toxic in contact with skin and H314 — Causes severe skin burns and eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 105827-91-6
Jingsj CID: J-1136499-1
Molecular Formula: C₄H₃Cl₂NS
Molecular Weight: 168.044 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	31ºC
Boiling Point	268.6±32.0 °C at 760 mmHg
Density	1.5±0.1 g/cm3
Flash Point	116.3±25.1 °C
Exact Mass	166.936325
PSA	41.13000
LogP	1.26
Vapor Pressure	0.0±0.5 mmHg at 25°C
Refractive Index	1.584
Storage Conditions	2-8°C

GHS Safety & Compliance

Corrosion / Acute Toxicity / Environmental HazardSignal word: Danger

H302 — Harmful if swallowed
H311 — Toxic in contact with skin
H314 — Causes severe skin burns and eye damage
H317 — May cause an allergic skin reaction
H411 — Toxic to aquatic life with long lasting effects

Customs & Trade Information

HS Code	2934100090
Summary	2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 2-Chloro-5-(chloromethyl)thiazole?

The CAS number of 2-Chloro-5-(chloromethyl)thiazole is 105827-91-6.

What are the molecular formula and molecular weight of 2-Chloro-5-(chloromethyl)thiazole?

2-Chloro-5-(chloromethyl)thiazole has molecular formula C4H3Cl2NS and molecular weight 168.044 g/mol.

Is 2-Chloro-5-(chloromethyl)thiazole hazardous?

2-Chloro-5-(chloromethyl)thiazole has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H311 — Toxic in contact with skin; H314 — Causes severe skin burns and eye damage.

What are the upstream and downstream products of 2-Chloro-5-(chloromethyl)thiazole?

For 2-Chloro-5-(chloromethyl)thiazole, Upstream Products: 2-chloro-3-isothiocyanato-prop-1-ene, (2-Chloro-1,3-thiazol-5-yl)methanol, Allyl isothiocyanate; Downstream Products: (2-Chloro-1,3-thiazol-5-yl)methanol, 1-(2-Chloro-1,3-thiazol-5-yl)methanamine, Thiamethoxam.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "2-Chloro-5-(chloromethyl)thiazole (CAS 105827-91-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1136499-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.