Skip to main content

L-4-Hydroxyproline methyl ester hydrochloride

Also known as: trans-4-Hydroxy-L-proline methyl ester hydrochloride, H-Hyp-OMe hydrochloride, Methyl (2S,4R)-4-hydroxypyrrolidine-2-carboxylate hydrochloride, (2S,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride, trans-4-Hydroxy-L-proline methylester hydrochloride, 4-hydroxy-2-pyrrolidinecarboxylic acid methyl ester hydrochloride, L-4-HYDROXYPROLINE METHYL ESTER HYDROCHLORIDE SALT, Methyl 4-hydroxyprolinate hydrochloride (1:1), Proline, 4-hydroxy-, methyl ester, hydrochloride (1:1), Hydroxyproline-OMe HCl

L-4-Hydroxyproline methyl ester hydrochloride (CAS 40216-83-9) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C6H12ClNO3 and a molecular weight of 181.617 g/mol. Key properties include a boiling point of 247.2ºC at 760 mmHg and a flash point of 103.3ºC. It is listed by 3 suppliers, 2 of which publish reference prices, from 0.64 to 1.10 CNY. Record last updated Aug 21, 2026.

CAS No.
40216-83-9
Jingsj CID
J-1135664-6
Molecular Formula
C6H12ClNO3
Molecular Weight
181.617 g/mol
Category
Organic Acids
Last updated
8/21/2026
In Stock

Supplier Offers

3Request a quote
Filter:
SupplierPurity / PackBase PriceUnit PriceOrigin
In Stock
95%
500g
¥320.00
$0.1 /gBest
¥0.64/g CNY
CN China
MOQ 标准
Made to Order
95%
500g
¥320.00
$0.1 /g
¥0.64/g CNY
CN China
MOQ 500g
Made to Order
95%
250g
¥180.00
$0.11 /g
¥0.72/g CNY
CN China
MOQ 250g

Physicochemical Properties

Boiling Point247.2ºC at 760 mmHg
Flash Point103.3ºC
Exact Mass181.050568
PSA58.56000
LogP0.01300

Activity & Biological Data

TargetNon-cleavable
Additional Information[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Customs & Trade Information

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of L-4-Hydroxyproline methyl ester hydrochloride?

The CAS number of L-4-Hydroxyproline methyl ester hydrochloride is 40216-83-9.

What are the molecular formula and molecular weight of L-4-Hydroxyproline methyl ester hydrochloride?

L-4-Hydroxyproline methyl ester hydrochloride has molecular formula C6H12ClNO3 and molecular weight 181.617 g/mol.

Which suppliers offer L-4-Hydroxyproline methyl ester hydrochloride?

3 supplier(s) listed; reference unit price ¥0.64–1.10 /g.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "L-4-Hydroxyproline methyl ester hydrochloride (CAS 40216-83-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1135664-6 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.