K-7174 (dihydrochloride)

Also known as: 1,4-Bis[(4E)-5-(3,4,5-trimethoxyphenyl)-4-penten-1-yl]-1,4-diazepane, K-7174 (dihydrochloride)

K-7174 (dihydrochloride) (CAS 191089-60-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C33H50Cl2N2O6 and a molecular weight of 641.67 g/mol. Key properties include a boiling point of 689.9±55.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 171.2±28.7 °C. It is listed by 1 supplier, from 66.00 to 136.00 CNY. Record last updated Nov 2, 2026.

CAS No.: 191089-60-8
Jingsj CID: J-1135201-3
Molecular Formula: C₃₃H₅₀Cl₂N₂O₆
Molecular Weight: 641.67 g/mol
Category: Organic Acids
Last updated: 11/2/2026

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Supplier	Purity / Pack	Base Price	Unit Price	Origin
Maikuo Made to Order	99% 25mg	¥1,650.00	$9.88 /mgBest ¥66.00/mg CNY	CN China MOQ 25mg	View Product
Maikuo Made to Order	98% 50mg	¥4,680.00	$14.01 /mg ¥93.60/mg CNY	CN China MOQ 50mg	View Product
Maikuo Made to Order	99% 5mg	¥680.00	$20.35 /mg ¥136.00/mg CNY	CN China MOQ 5mg	View Product

Physicochemical Properties

Boiling Point	689.9±55.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	171.2±28.7 °C
LogP	5.61
InChIKey	JKAQFPBRMVEHBD-CHBZAFCASA-N
SMILES	COc1cc(C=CCCCN2CCCN(CCCC=Cc3cc(OC)c(OC)c(OC)c3)CC2)cc(OC)c1OC.Cl.Cl
Vapor Pressure	0.0±2.2 mmHg at 25°C
Refractive Index	1.552
Storage Conditions	2-8℃

Activity & Biological Data

Additional Information	[1].、Umetani M, et al. A novel cell adhesion inhibitor, K-7174, reduces the endothelial VCAM-1 induction by inflammatory cytokines, acting through the regulation of GATA. Biochem Biophys Res Commun. 2000 Jun 7;272(2):370-4.、[2].、Imagawa S, et al. A GATA-specific inhibitor (K-7174) rescues anemia induced by IL-1beta, TNF-alpha, or L-NMMA. FASEB J. 2003 Sep;17(12):1742-4.、[3].、Shimada T, et al. Unexpected blockade of adipocyte differentiation by K-7174: implication for endoplasmic reticulum stress. Biochem Biophys Res Commun. 2007 Nov 16;363(2):355-60.、[4].、Kikuchi J, et al. The novel orally active proteasome inhibitor K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases. J Biol Chem. 2013 Aug 30;288(35):25593-602.

Additional Information

[1].、Umetani M, et al. A novel cell adhesion inhibitor, K-7174, reduces the endothelial VCAM-1 induction by inflammatory cytokines, acting through the regulation of GATA. Biochem Biophys Res Commun. 2000 Jun 7;272(2):370-4.、[2].、Imagawa S, et al. A GATA-specific inhibitor (K-7174) rescues anemia induced by IL-1beta, TNF-alpha, or L-NMMA. FASEB J. 2003 Sep;17(12):1742-4.、[3].、Shimada T, et al. Unexpected blockade of adipocyte differentiation by K-7174: implication for endoplasmic reticulum stress. Biochem Biophys Res Commun. 2007 Nov 16;363(2):355-60.、[4].、Kikuchi J, et al. The novel orally active proteasome inhibitor K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases. J Biol Chem. 2013 Aug 30;288(35):25593-602.

Frequently Asked Questions

What is the CAS number of K-7174 (dihydrochloride)?

The CAS number of K-7174 (dihydrochloride) is 191089-60-8.

What are the molecular formula and molecular weight of K-7174 (dihydrochloride)?

K-7174 (dihydrochloride) has molecular formula C33H50Cl2N2O6 and molecular weight 641.67 g/mol.

Which suppliers offer K-7174 (dihydrochloride)?

1 supplier(s) listed; reference unit price ¥66.00–136.00 /mg.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 11/2/2026

How to cite: Jingsj. "K-7174 (dihydrochloride) (CAS 191089-60-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1135201-3 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.