N-(3-Chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4-quinazolinamine

4-[(3-氯-4-氟苯基)氨基]-6-硝基-7-((S)-四氢呋喃-3-基氧基)-喹唑啉

Also known as: 7-((S)-tetrahydrofuran-3-yloxy)-4-(3-chloro-4-fluorophenyl)amino-6-nitroquinazoline, (S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-[(tetrahydrofuran-3-yl)oxy]quinazolin-4-amine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[(3S)-oxolan-3-yl]oxyquinazolin-4-amine, Afatinib intermediate 1, 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-

N-(3-Chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4-quinazolinamine (CAS 314771-88-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C18H14ClFN4O4 and a molecular weight of 404.780 g/mol. It is also known as 7-((S)-tetrahydrofuran-3-yloxy)-4-(3-chloro-4-fluorophenyl)amino-6-nitroquinazoline, (S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-[(tetrahydrofuran-3-yl)oxy]quinazolin-4-amine and N-(3-chloro-4-fluorophenyl)-6-nitro-7-[(3S)-oxolan-3-yl]oxyquinazolin-4-amine. Key properties include a boiling point of 585.0±50.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 307.6±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.

314771-88-5

Jingsj CID

J-1123487-6

Molecular Formula

C₁₈H₁₄ClFN₄O₄

Chinese Name

4-[(3-氯-4-氟苯基)氨基]-6-硝基-7-((S)-四氢呋喃-3-基氧基)-喹唑啉

Molecular Weight

404.780 g/mol

Category

Pharma Intermediates

Last updated

8/21/2026