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Neotame

Also known as: (3S)-3-(3,3-dimethylbutylamino)-4-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid, (3S,4E)-3-[(3,3-Dimethylbutyl)amino]-4-hydroxy-4-{[(2S)-1-methoxy-1-oxo-3-phenyl-2-propanyl]imino}butanoic acid, (S)-3-((3,3-DiMethylbutyl)aMino)-4-(((S)-1-Methoxy-1-oxo-3-phenylpropan-2-yl)aMino)-4-oxobutanoic acid, (S)-3-((3,3-Dimethylbutyl)amino)-4-(((S)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amino)-4-oxobutanoic ac, (S)-3-((3,3-Dimethylbutyl)amino)-4-(((S)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amino)-4-oxobutanoic acid, E961, L-PHENYLALANINE, N-[N-(3,3-DIMETHYLBUTYL)-L-.ALPHA.-ASPARTYL]-, 1-METHYL ESTER, L-Phenylalanine, N-[(2S)-3-carboxy-2-[(3,3-dimethylbutyl)amino]-1-hydroxypropylidene]-, methyl ester, (E)-, L-Phenylalanine,N-(3,3-diMethylbutyl)-L-a-aspartyl-,2-Methyl ester, L-phenylalanine, N-(3,3-dimethylbutyl)-L-α-aspartyl-, methyl ester, Methyl N-(3,3-dimethylbutyl)-L-α-aspartyl-L-phenylalaninate, Methyl N-(3,3-dimethylbutyl)-L-α-aspartylphenylalaninate, N-(3,3-Dimethylbutyl)-L-a-aspartyl-L-phenylalanine Methyl Ester, N-(3,3-dimethylbutyl)-L-aspartyl-L-phenylalanine methyl ester, N-(N-(3,3-Dimethylbutyl)-L-alpha-aspartyl)-L-phenylalanine 1-methyl ester, N-[N-(3,3-dimethylbutyl)-L--aspartyl]-L-phenylalanine 1-methyl ester, N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine methyl ester, NEOTAME, NEOTAME, Neutame

Neotame (CAS 165450-17-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H30N2O5 and a molecular weight of 378.463 g/mol. Key properties include a melting point of 80.9-83.4ºC, a boiling point of 535.8±60.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 277.9±32.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
165450-17-9
Jingsj CID
J-1115040-6
Molecular Formula
C20H30N2O5
Molecular Weight
378.463 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point80.9-83.4ºC
Boiling Point535.8±60.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point277.9±32.9 °C
Exact Mass378.215485
PSA104.73000
LogP4.73
Vapor Pressure0.0±1.5 mmHg at 25°C
Refractive Index1.530

Activity & Biological Data

Additional Information[1]. Liang Chi, et al. Effects of the Artificial Sweetener Neotame on the Gut Microbiome and Fecal Metabolites in Mice. Molecules. 2018 Feb 9;23(2):367. [2]. Anuradha Kumari, et al. Stability of Aspartame and Neotame in Pasteurized and In-Bottle Sterilized Flavoured Milk. Food Chem. 2016 Apr 1;196:533-8.

Customs & Trade Information

HS Code2924299090
Summary2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Neotame?

The CAS number of Neotame is 165450-17-9.

What are the molecular formula and molecular weight of Neotame?

Neotame has molecular formula C20H30N2O5 and molecular weight 378.463 g/mol.

What are the upstream and downstream products of Neotame?

For Neotame, Upstream Products: 3,3-Dimethylbutanal, Aspartame.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Neotame (CAS 165450-17-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1115040-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.