Edaravone
Also known as: 1-Phenyl-3-methyl-2-pyrazolin-5-one, 1-Phenyl-3-methyl-5-pyrazolone, 1-Phenyl-3-methyl-5-oxo-2-pyrazoline, 3-Methyl-1-phenyl-2-pyrazolin-5-one, 3-Methyl-1-phenyl-5-pyrazolone, 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one, 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one, 5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, MCI-186, Monopyrazolone, PMP
Edaravone (CAS 89-25-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C10H10N2O and a molecular weight of 174.199 g/mol. Key properties include a melting point of 126-128 °C(lit.), a boiling point of 333.0±11.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 155.2±19.3 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 89-25-8
- Jingsj CID
- J-1111290-6
- Molecular Formula
- C10H10N2O
- Molecular Weight
- 174.199 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 126-128 °C(lit.) |
|---|---|
| Boiling Point | 333.0±11.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 155.2±19.3 °C |
| Exact Mass | 174.079315 |
| PSA | 32.67000 |
| LogP | 0.44 |
| Vapor Pressure | 0.0±0.7 mmHg at 25°C |
| Refractive Index | 1.606 |
| Additional Property | 3 g/L (20 ºC) |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Additional Information | [1]. Yoshida, H., et al. Neuroprotective effects of edaravone: a novel free radical scavenger in cerebrovascular injury. CNS Drug Rev, 2006. 12(1): p. 9-20. [2]. Okamura, K., et al. Edaravone, a free radical scavenger, attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia. Neurol Res, 2013. [3]. Garcia CA, et al. Edaravone reduces astrogliosis and apoptosis in young rats with kaolin-induced hydrocephalus. Childs Nerv Syst. 2016 Dec 17. [Epub ahead of print] [4]. Bai X, et al. Protective Effect of Edaravone on Glutamate-Induced Neurotoxicity in Spiral Ganglion Neurons. Neural Plast. 2016;2016:4034218. Epub 2016 Nov 10. |
|---|
Customs & Trade Information
| HS Code | 2933199090 |
|---|---|
| Summary | 2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Edaravone?
The CAS number of Edaravone is 89-25-8.
What are the molecular formula and molecular weight of Edaravone?
Edaravone has molecular formula C10H10N2O and molecular weight 174.199 g/mol.
Is Edaravone hazardous?
Edaravone has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.
What are the upstream and downstream products of Edaravone?
For Edaravone, Upstream Products: Ethyl acetoacetate, Methyl acetoacetate, Phenylhydrazine; Downstream Products: 4-Benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one, Antipyrine, 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carbonitrile.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Edaravone (CAS 89-25-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1111290-6 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.