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N-Iodosuccinimide

Also known as: NIS, 1-Iodo-2,5-pyrrolidinedione, 1-Iodopyrrolidine-2,5-dione, 2,5-Pyrrolidinedione, 1-iodo-, Iodosuccinimide, succinimide, N-iodo-, 1-iodo-5-pyrrolidinedione, N-Iodo succinimide

N-Iodosuccinimide (CAS 516-12-1) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C4H4INO2 and a molecular weight of 224.984 g/mol. Key properties include a melting point of 202-206 °C(lit.), a boiling point of 249.6±23.0 °C at 760 mmHg, a density of 2.3±0.1 g/cm3 and a flash point of 104.8±22.6 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
516-12-1
Jingsj CID
J-1103926-2
Molecular Formula
C4H4INO2
Molecular Weight
224.984 g/mol
Category
Organic Bases
Last updated
8/21/2026

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Physicochemical Properties

Melting Point202-206 °C(lit.)
Boiling Point249.6±23.0 °C at 760 mmHg
Density2.3±0.1 g/cm3
Flash Point104.8±22.6 °C
Exact Mass224.928665
PSA37.38000
LogP-0.21
Vapor Pressure0.0±0.5 mmHg at 25°C
Refractive Index1.653
Additional Propertydecomposes

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2925190090
Summary2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of N-Iodosuccinimide?

The CAS number of N-Iodosuccinimide is 516-12-1.

What are the molecular formula and molecular weight of N-Iodosuccinimide?

N-Iodosuccinimide has molecular formula C4H4INO2 and molecular weight 224.984 g/mol.

Is N-Iodosuccinimide hazardous?

N-Iodosuccinimide has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of N-Iodosuccinimide?

For N-Iodosuccinimide, Upstream Products: N-Bromosuccinimide, N-Chlorosuccinimide, Succinimide; Downstream Products: 4-Amino-3-iodobenzonitrile, Succinimide, 5-Bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "N-Iodosuccinimide (CAS 516-12-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1103926-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.