Naphthol AS-E

Also known as: N-(4-chlorophenyl)-3-hydroxynaphthalene-2-carboxamide, 4'-Chloro-3-hydroxy-2-naphthanilide, AZOIC COUPLING COMPONENT 10, C.I. 37510, C.I. Azoic Coupling Component 10, Napthol AS-E, Naphtanilide E, Naphtazol E, Naphtoelan E, Sanatol E, Daito Grounder E, AcnaNaphtholPC, Amanil Naphthol AS-E, Cibanaphthol RC, 3-hydroxy-naphthalene-2-carboxylic acid 4-chloro-anilide, 3-Hydroxy-[2]naphthoesaeure-(4-chlor-anilid), 3-hydroxy-[2]naphthoic acid-(4-chloro-anilide), MFCD00021639, EINECS 202-189-7

Naphthol AS-E (CAS 92-78-4) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C17H12ClNO2 and a molecular weight of 297.73600 g/mol. Key properties include a melting point of 255°C, a boiling point of 416.5ºC at 760 mmHg, a density of 1.399 g/cm3 and a flash point of 205.7ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 92-78-4
Jingsj CID: J-1101780-4
Molecular Formula: C₁₇H₁₂ClNO₂
Molecular Weight: 297.73600 g/mol
Category: Alcohols
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	255°C
Boiling Point	416.5ºC at 760 mmHg
Density	1.399 g/cm3
Flash Point	205.7ºC
Exact Mass	297.05600
PSA	49.33000
LogP	4.52410
Refractive Index	1.735

Activity & Biological Data

Target	KIX-KID:2.26 μM (IC50)
Additional Information	[1]. Fuchun Xie, et al. Synthesis and Evaluation of an O-Aminated Naphthol AS-E as a Prodrug of CREB-mediated Gene Transcription Inhibition. Lett Org Chem. 2013 Jun;10(5):380-384. [2]. Bingbing X Li, et al. Discovery of a small-molecule inhibitor of the KIX-KID interaction. Chembiochem. 2009 Nov 23;10(17):2721-4.

Customs & Trade Information

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Naphthol AS-E?

The CAS number of Naphthol AS-E is 92-78-4.

What are the molecular formula and molecular weight of Naphthol AS-E?

Naphthol AS-E has molecular formula C17H12ClNO2 and molecular weight 297.73600 g/mol.

What are the upstream and downstream products of Naphthol AS-E?

For Naphthol AS-E, Upstream Products: 4-Chloroaniline, 3-Hydroxy-2-naphthoic acid, 4-Chlorophenyl isothiocyanate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Naphthol AS-E (CAS 92-78-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1101780-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.