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4,4'-Diphenylmethane diisocyanate

Also known as: Methylene diphenyl diisocyanate, 4,4'-MDI, 4,4'-Methylenebis(phenyl isocyanate), Methylenediphenyl 4,4'-diisocyanate, 1,1'-Methylenebis(4-isocyanatobenzene), Bis(4-isocyanatophenyl)methane, Isonate, Rubinate 44, Desmodur 44, Caradate 30, Hylene M50, p,p'-Diphenylmethane diisocyanate

4,4'-Diphenylmethane diisocyanate (CAS 101-68-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C15H10N2O2 and a molecular weight of 250.252 g/mol. Key properties include a melting point of 38-44 °C, a boiling point of 392 ºC, a density of 1.19 and a flash point of 196 ºC. It is classified under GHS with signal word Danger and hazard statements H315 — Causes skin irritation, H317 — May cause an allergic skin reaction and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
101-68-8
Jingsj CID
J-1100471-0
Molecular Formula
C15H10N2O2
Molecular Weight
250.252 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point38-44 °C
Boiling Point392 ºC
Density1.19
Flash Point196 ºC
Exact Mass250.074234
PSA58.86000
LogP4.93
Vapor Pressure0.0±0.8 mmHg at 25°C
Refractive Index1.588
Additional Propertydecomposes
Additional Property37℃

GHS Safety & Compliance

Irritant / Health HazardSignal word: Danger
  • H315 — Causes skin irritation
  • H317 — May cause an allergic skin reaction
  • H319 — Causes serious eye irritation
  • H332 — Harmful if inhaled
  • H334 — May cause allergy or asthma symptoms if inhaled
  • H335 — May cause respiratory irritation
  • H351 — Suspected of causing cancer
  • H373 — May cause damage to organs through prolonged exposure

Customs & Trade Information

HS Code2929109000
Summary2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 4,4'-Diphenylmethane diisocyanate?

The CAS number of 4,4'-Diphenylmethane diisocyanate is 101-68-8.

What are the molecular formula and molecular weight of 4,4'-Diphenylmethane diisocyanate?

4,4'-Diphenylmethane diisocyanate has molecular formula C15H10N2O2 and molecular weight 250.252 g/mol.

Is 4,4'-Diphenylmethane diisocyanate hazardous?

4,4'-Diphenylmethane diisocyanate has GHS signal word Danger and hazard statements H315 — Causes skin irritation; H317 — May cause an allergic skin reaction; H319 — Causes serious eye irritation.

What are the upstream and downstream products of 4,4'-Diphenylmethane diisocyanate?

For 4,4'-Diphenylmethane diisocyanate, Upstream Products: 4,4'-Methylenedianiline, Diphenyl (methylenedi-4,1-phenylene)dicarbamate; Downstream Products: Diphenyl (methylenedi-4,1-phenylene)dicarbamate, Triethyl phosphate, 1,1,1',1'-Tetramethyl-4,4'-(methylenedi-p-phenylene)disemicarbazide.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "4,4'-Diphenylmethane diisocyanate (CAS 101-68-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1100471-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.