(S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine

N4-(3-氯-4-氟苯基)-7-[[(3S)-四氢-3-呋喃基]氧基]-4,6-喹唑啉二胺

Also known as: QC-4224, Afatinib impurity 2, N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine, N4-(3-Chloro-4-fluorophenyl)-7-[(3S)-tetrahydro-3-furanyloxy]-4,6-quinazolinediamine, 4,6-Quinazolinediamine, N-(3-chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-, 4,6-Quinazolinediamine, N4-(3-chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-, 6-Amino-4-[(3-chloro-4-fluorophenyl)amino]-7-[[(S)-tetrahydro-3-furanyl]oxy]quinazoline, Afatinib-1, Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl

(S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine (CAS 314771-76-1) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C18H16ClFN4O2 and a molecular weight of 374.797 g/mol. It is also known as QC-4224, Afatinib impurity 2 and N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine. Key properties include a boiling point of 559.0±50.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 291.9±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.

314771-76-1

Jingsj CID

J-1091963-9

Molecular Formula

C₁₈H₁₆ClFN₄O₂

Chinese Name

N4-(3-氯-4-氟苯基)-7-[[(3S)-四氢-3-呋喃基]氧基]-4,6-喹唑啉二胺

Molecular Weight

374.797 g/mol

Category

Pharma Intermediates

Last updated

8/21/2026