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N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropanamide

Also known as: N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide, Bicalutamide Sulfide, Bicalutamide EP Impurity J, Bicalutamide Intermediate, 4-Cyano-3-(trifluoromethyl)-N-[3-(4-fluorophenylthio)-2-hydroxy-2-methylpropionyl]aniline, N-(4-Cyano-3-trifluoromethyl-phenyl)-3-(4-fluoro-phenylsulfanyl)-2-hydroxy-2-methyl-propionamide, (R,S)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropanamide, N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfanyl]-2-hydroxy-2-methylpropanamide, Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methyl-

N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropanamide (CAS 90356-78-8) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C18H14F4N2O2S and a molecular weight of 398.375 g/mol. Key properties include a melting point of 109-111°C, a boiling point of 565.6±50.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 295.9±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
90356-78-8
Jingsj CID
J-1090297-3
Molecular Formula
C18H14F4N2O2S
Molecular Weight
398.375 g/mol
Category
Organic Bases
Last updated
8/21/2026

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Physicochemical Properties

Melting Point109-111°C
Boiling Point565.6±50.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point295.9±30.1 °C
Exact Mass398.071198
PSA98.42000
LogP5.69
Vapor Pressure0.0±1.6 mmHg at 25°C
Refractive Index1.585
Storage ConditionsRefrigerator

Frequently Asked Questions

What is the CAS number of N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropanamide?

The CAS number of N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropanamide is 90356-78-8.

What are the molecular formula and molecular weight of N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropanamide?

N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropanamide has molecular formula C18H14F4N2O2S and molecular weight 398.375 g/mol.

What are the upstream and downstream products of N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropanamide?

For N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropanamide, Upstream Products: 4-Fluorothiophenol, N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide, 3-(4-Fluorophenylthio)-2-hydroxy-2-methylpropanoic acid; Downstream Products: Bicalutamide, Bicalutamide Sulfoxide.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropanamide (CAS 90356-78-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1090297-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.