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D-Pyroglutamic acid

Also known as: (R)-5-Oxopyrrolidine-2-carboxylic acid, 5-Oxo-D-proline, D-5-Oxoproline, H-D-Pyr-OH, D-Pyr-OH, (R)-(+)-2-Pyrrolidinone-5-carboxylic acid, D-(+)-Pyroglutamic acid, Pidolic acid (D-)

D-Pyroglutamic acid (CAS 4042-36-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C5H7NO3 and a molecular weight of 129.114 g/mol. Key properties include a melting point of 155-162ºC, a boiling point of 453.1±38.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 227.8±26.8 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
4042-36-8
Jingsj CID
J-10825-8
Molecular Formula
C5H7NO3
Molecular Weight
129.114 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point155-162ºC
Boiling Point453.1±38.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point227.8±26.8 °C
Exact Mass129.042587
PSA66.40000
LogP-2.39
Vapor Pressure0.0±2.4 mmHg at 25°C
Refractive Index1.512

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2933790090
Summary2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of D-Pyroglutamic acid?

The CAS number of D-Pyroglutamic acid is 4042-36-8.

What are the molecular formula and molecular weight of D-Pyroglutamic acid?

D-Pyroglutamic acid has molecular formula C5H7NO3 and molecular weight 129.114 g/mol.

Is D-Pyroglutamic acid hazardous?

D-Pyroglutamic acid has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of D-Pyroglutamic acid?

For D-Pyroglutamic acid, Upstream Products: (R)-(-)-5-(Hydroxymethyl)-2-pyrrolidinone, Methyl (R)-(-)-2-pyrrolidinone-5-carboxylate, D(-)-Glutamic acid; Downstream Products: Fasoracetam, D(-)-Glutamic acid, (5R)-5-(bromomethyl)pyrrolidin-2-one.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "D-Pyroglutamic acid (CAS 4042-36-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-10825-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.