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HEPES sodium salt

Also known as: sodium 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonate, 2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulfonic acid sodium salt, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid monosodium salt, HEPES sodium, HEPES-Na, HEPES sodium salt hydrate

HEPES sodium salt (CAS 75277-39-3) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C8H17N2NaO4S and a molecular weight of 260.286 g/mol. Key property: a melting point of 234ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
75277-39-3
Jingsj CID
J-1081688-3
Molecular Formula
C8H17N2NaO4S
Molecular Weight
260.286 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point234ºC
Exact Mass260.080658
PSA92.29000
Additional PropertyH2O: 1 M at 20 °C, clear, colorless

Activity & Biological Data

Additional Information[1]. Suzuki T, et al. Nonvolatile buffer coating of titanium to prevent its biological aging and for drug delivery. Biomaterials. 2010;31(18):4818-4828. [2]. Sledź P, et al. An experimental charge density of HEPES. Acta Crystallogr B. 2010;66(Pt 4):482-492. [3]. https://pubmed.ncbi.nlm.nih.gov/20631430/

Customs & Trade Information

HS Code2933599090
Summary2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of HEPES sodium salt?

The CAS number of HEPES sodium salt is 75277-39-3.

What are the molecular formula and molecular weight of HEPES sodium salt?

HEPES sodium salt has molecular formula C8H17N2NaO4S and molecular weight 260.286 g/mol.

What are the upstream and downstream products of HEPES sodium salt?

For HEPES sodium salt, Upstream Products: 1-(2-Hydroxyethyl)piperazine, Sodium isethionate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "HEPES sodium salt (CAS 75277-39-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1081688-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.