2,2,2-Trifluoroacetamide
Also known as: Trifluoroacetamide, Acetamide, 2,2,2-trifluoro-, N-Trifluoroacetamide, Trifluoroacetyl amine
2,2,2-Trifluoroacetamide (CAS 354-38-1) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C2H2F3NO and a molecular weight of 113.039 g/mol. Key properties include a melting point of 65-70 °C(lit.), a boiling point of 162.5±35.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 52.1±25.9 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 354-38-1
- Jingsj CID
- J-1066574-4
- Molecular Formula
- C2H2F3NO
- Molecular Weight
- 113.039 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 65-70 °C(lit.) |
|---|---|
| Boiling Point | 162.5±35.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 52.1±25.9 °C |
| Exact Mass | 113.008850 |
| PSA | 43.09000 |
| LogP | 0.17 |
| Vapor Pressure | 2.2±0.3 mmHg at 25°C |
| Refractive Index | 1.314 |
| Storage Conditions | Store at RT. |
| Additional Property | 460 g/L (20 ºC) |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Customs & Trade Information
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of 2,2,2-Trifluoroacetamide?
The CAS number of 2,2,2-Trifluoroacetamide is 354-38-1.
What are the molecular formula and molecular weight of 2,2,2-Trifluoroacetamide?
2,2,2-Trifluoroacetamide has molecular formula C2H2F3NO and molecular weight 113.039 g/mol.
Is 2,2,2-Trifluoroacetamide hazardous?
2,2,2-Trifluoroacetamide has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of 2,2,2-Trifluoroacetamide?
For 2,2,2-Trifluoroacetamide, Upstream Products: Ethyl trifluoroacetate, Oxalyl chloride, Trifluoroacetic acid; Downstream Products: 2,2,2-Trifluoro-N-(4-methoxyphenyl)acetamide, 3-Phenoxy-1,2-propanediol, N-(Hydroxymethyl)trifluoroacetamide.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "2,2,2-Trifluoroacetamide (CAS 354-38-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1066574-4 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.