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N-Methyl-bis(trifluoroacetamide)

Also known as: MBTFA, N-Methylbis(trifluoroacetamide), N-Methylbis(trifluoroacetyl)amine, N-Methylbis(trifluoroacetyl)imide, N-Methyl-N-bis(trifluoroacetamide), N,N-Bis(trifluoroacetyl)methylamine, 2,2,2-Trifluoro-N-methyl-N-(trifluoroacetyl)acetamide, 2,2,2-trifluoro-N-methyl-N-(2,2,2-trifluoroacetyl)acetamide, Acetamide, 2,2,2-trifluoro-N-methyl-N-(trifluoroacetyl)-, Acetamide, 2,2,2-trifluoro-N-methyl-N-(2,2,2-trifluoroacetyl)-, N-Methylbistrifluoracetamid, EINECS 211-680-5, MFCD00000412

N-Methyl-bis(trifluoroacetamide) (CAS 685-27-8) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C5H3F6NO2 and a molecular weight of 223.073 g/mol. Key properties include a boiling point of 121.0±0.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 42.2±0.0 °C. It is classified under GHS with signal word Danger and hazard statements H226 — Flammable liquid and vapour and H314 — Causes severe skin burns and eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
685-27-8
Jingsj CID
J-1065959-3
Molecular Formula
C5H3F6NO2
Molecular Weight
223.073 g/mol
Category
Organic Bases
Last updated
8/21/2026
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Physicochemical Properties

Boiling Point121.0±0.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Flash Point42.2±0.0 °C
Exact Mass223.006805
PSA37.38000
LogP2.20
Vapor Pressure14.9±0.2 mmHg at 25°C
Refractive Index1.333

GHS Safety & Compliance

Flammable / CorrosionSignal word: Danger
  • H226 — Flammable liquid and vapour
  • H314 — Causes severe skin burns and eye damage

Frequently Asked Questions

What is the CAS number of N-Methyl-bis(trifluoroacetamide)?

The CAS number of N-Methyl-bis(trifluoroacetamide) is 685-27-8.

What are the molecular formula and molecular weight of N-Methyl-bis(trifluoroacetamide)?

N-Methyl-bis(trifluoroacetamide) has molecular formula C5H3F6NO2 and molecular weight 223.073 g/mol.

Is N-Methyl-bis(trifluoroacetamide) hazardous?

N-Methyl-bis(trifluoroacetamide) has GHS signal word Danger and hazard statements H226 — Flammable liquid and vapour; H314 — Causes severe skin burns and eye damage.

What are the upstream and downstream products of N-Methyl-bis(trifluoroacetamide)?

For N-Methyl-bis(trifluoroacetamide), Upstream Products: Trifluoroacetyl chloride, N-Methyl-2,2,2-trifluoroacetamide; Downstream Products: phenyl trifluoroacetate, 3-Methyl-1-(trifluoroacetyl)pyrrolidine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "N-Methyl-bis(trifluoroacetamide) (CAS 685-27-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1065959-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.