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N-Methylisatoic anhydride

Also known as: 1-methyl-2H-3,1-benzoxazine-2,4(1H)-dione, 1-methyl-1H-benzo[d][1,3]oxazine-2,4-dione, 1-Methyl-4H-3,1-benzoxazine-2(1H),4-dione, N-Methylisatoic acid anhydride, MIA, NSC 76087, MFCD00006815

N-Methylisatoic anhydride (CAS 10328-92-4) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C9H7NO3 and a molecular weight of 177.15700 g/mol. Key properties include a melting point of 165 °C (dec.)(lit.), a boiling point of 297.5ºC at 760 mmHg, a density of 1.348 g/cm3 and a flash point of 133.7ºC. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
10328-92-4
Jingsj CID
J-10440-9
Molecular Formula
C9H7NO3
Molecular Weight
177.15700 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point165 °C (dec.)(lit.)
Boiling Point297.5ºC at 760 mmHg
Density1.348 g/cm3
Flash Point133.7ºC
Exact Mass177.04300
PSA52.21000
LogP0.49170
Additional Property6.1 (vs air)
Vapor Pressure0.00135mmHg at 25°C
Refractive Index1.583

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Ursuegui S, et al. Biotin-conjugated N-methylisatoic anhydride: a chemical tool for nucleic acid separation by selective 2'-hydroxyl acylation of RNA. Chem Commun (Camb). 2014 Jun 1;50(43):5748-51.

Customs & Trade Information

HS Code2934999090
Summary2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of N-Methylisatoic anhydride?

The CAS number of N-Methylisatoic anhydride is 10328-92-4.

What are the molecular formula and molecular weight of N-Methylisatoic anhydride?

N-Methylisatoic anhydride has molecular formula C9H7NO3 and molecular weight 177.15700 g/mol.

Is N-Methylisatoic anhydride hazardous?

N-Methylisatoic anhydride has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of N-Methylisatoic anhydride?

For N-Methylisatoic anhydride, Upstream Products: Isatoic anhydride, iodomethane, N-Methylaniline; Downstream Products: ethyl 2-(methylamino)benzoate, leucoline, 10-Methyl-9(10H)-acridone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "N-Methylisatoic anhydride (CAS 10328-92-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-10440-9 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.