N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide)
Also known as: Comins' Reagent, 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine, N-(5-Chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]methanesulfonamide, 2-(N,N-Bis(trifluoromethylsulfonyl)amino)-5-chloropyridine, Comins Triflating, MFCD00191833
N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide) (CAS 145100-51-2) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C7H3ClF6N2O4S2 and a molecular weight of 392.683 g/mol. Key properties include a melting point of 45-47 °C(lit.), a boiling point of 358.3±52.0 °C at 760 mmHg, a density of 1.9±0.1 g/cm3 and a flash point of 170.5±30.7 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 145100-51-2
- Jingsj CID
- J-10380-0
- Molecular Formula
- C7H3ClF6N2O4S2
- Molecular Weight
- 392.683 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 45-47 °C(lit.) |
|---|---|
| Boiling Point | 358.3±52.0 °C at 760 mmHg |
| Density | 1.9±0.1 g/cm3 |
| Flash Point | 170.5±30.7 °C |
| Exact Mass | 391.912689 |
| PSA | 101.17000 |
| LogP | 2.68 |
| Vapor Pressure | 0.0±0.8 mmHg at 25°C |
| Refractive Index | 1.499 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Customs & Trade Information
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
Frequently Asked Questions
What is the CAS number of N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide)?
The CAS number of N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide) is 145100-51-2.
What are the molecular formula and molecular weight of N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide)?
N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide) has molecular formula C7H3ClF6N2O4S2 and molecular weight 392.683 g/mol.
Is N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide) hazardous?
N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide) has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide)?
For N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide), Upstream Products: 2-Amino-5-chloropyridine, Trifluoromethanesulfonic anhydride; Downstream Products: 3,6-Dihydro-2H-pyran-4-yl trifluoromethanesulfonate, 8-Boc-3-(trifluoromethylsulfonyloxy)-8-azabicyclo[3.2.1]oct-3-ene, ethyl 4-(((trifluoromethyl)sulfonyl)oxy)cyclohex-3-ene-1-carboxylate.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide) (CAS 145100-51-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-10380-0 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.