BMS-378806

Also known as: BMS-806, 1-[(2R)-4-Benzoyl-2-methyl-1-piperazinyl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)-1,2-ethanedione, (R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione, 1,2-Ethanedione, 1-[(2R)-4-benzoyl-2-methyl-1-piperazinyl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)-, SINOVA SL-02580

BMS-378806 (CAS 357263-13-9) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C22H22N4O4 and a molecular weight of 406.435 g/mol. Key properties include a boiling point of 622.3ºC at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 330.2ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 357263-13-9
Jingsj CID: J-1003872-9
Molecular Formula: C₂₂H₂₂N₄O₄
Molecular Weight: 406.435 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	622.3ºC at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	330.2ºC
Exact Mass	406.164093
PSA	95.60000
LogP	0.73
Refractive Index	1.647
Storage Conditions	-20℃

Activity & Biological Data

Target	HIV[1]
Additional Information	[1]. Wang T, et al. Discovery of 4-benzoyl-1-[(4-methoxy-1H- pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): a novel HIV-1 attachment inhibitor that interferes with CD4-gp120 interactions. J Med Chem. 2003 Sep 25;46(20):4236-9. [2]. Ho HT, et al. Envelope conformational changes induced by human immunodeficiency virus type 1 attachment inhibitors prevent CD4 binding and downstream entry events. J Virol. 2006 Apr;80(8):4017-25. [3]. Guo Q, et al. Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactions. J Virol. 2003 Oct;77(19):10528-36.

Target

HIV[1]

Additional Information

[1]. Wang T, et al. Discovery of 4-benzoyl-1-[(4-methoxy-1H- pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): a novel HIV-1 attachment inhibitor that interferes with CD4-gp120 interactions. J Med Chem. 2003 Sep 25;46(20):4236-9. [2]. Ho HT, et al. Envelope conformational changes induced by human immunodeficiency virus type 1 attachment inhibitors prevent CD4 binding and downstream entry events. J Virol. 2006 Apr;80(8):4017-25. [3]. Guo Q, et al. Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactions. J Virol. 2003 Oct;77(19):10528-36.

Frequently Asked Questions

What is the CAS number of BMS-378806?

The CAS number of BMS-378806 is 357263-13-9.

What are the molecular formula and molecular weight of BMS-378806?

BMS-378806 has molecular formula C22H22N4O4 and molecular weight 406.435 g/mol.

What are the upstream and downstream products of BMS-378806?

For BMS-378806, Upstream Products: Methyl benzoate, 7-Azaindole, (R)-(-)-2-Methylpiperazine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "BMS-378806 (CAS 357263-13-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1003872-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.