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TTNPB

Also known as: Arotinoid Acid, Ro 13-7410, AGN-191183, AGN 191183, (E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl)benzoic acid, Benzoic acid, 4-[(1E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propen-1-yl]-, Lopac-T-3757, Tocris-0761, 4-[(1E)-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]benzoic acid, ARotinoic acid

TTNPB (CAS 71441-28-6) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C24H28O2 and a molecular weight of 348.478 g/mol. Key properties include a boiling point of 486.8±44.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 228.6±23.1 °C. It is classified under GHS with signal word Danger and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
71441-28-6
Jingsj CID
J-10028-1
Molecular Formula
C24H28O2
Molecular Weight
348.478 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point486.8±44.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point228.6±23.1 °C
Exact Mass348.208923
PSA37.30000
LogP8.62
Vapor Pressure0.0±1.3 mmHg at 25°C
Refractive Index1.579
Additional Propertychloroform/methanol: soluble9.80 - 10.20 mg/mL, clear, colorless to light yellow

GHS Safety & Compliance

Irritant / Health HazardSignal word: Danger
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation
  • H360 — May damage fertility or the unborn child

Activity & Biological Data

TargetIC50: 5.1 nM (RARα), 4.5 nM (RARβ), 9.3 nM (RARγ)[1]
Additional Information[1]. Pignatello MA, et al. Multiple factors contribute to the toxicity of the aromatic retinoid, TTNPB (Ro 13-7410): binding affinities and disposition. Toxicol Appl Pharmacol. 1997 Feb;142(2):319-27.

Frequently Asked Questions

What is the CAS number of TTNPB?

The CAS number of TTNPB is 71441-28-6.

What are the molecular formula and molecular weight of TTNPB?

TTNPB has molecular formula C24H28O2 and molecular weight 348.478 g/mol.

Is TTNPB hazardous?

TTNPB has GHS signal word Danger and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of TTNPB?

For TTNPB, Upstream Products: 4-Iodobenzoic acid, 1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone, 1,1,4,4-Tetramethyl-1,2,3,4-tetrahydronaphthalene.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "TTNPB (CAS 71441-28-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-10028-1 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.