MCOPPB三盐酸盐

别名 / 同义词: 1-[1-(1-甲基环辛基)-4-哌啶基]-2-[(3R)-3-哌啶基]-1H-苯并咪唑三盐酸盐、1-(1-(1-甲基环辛基)哌啶-4-基)-2-(哌啶-3-基)-1H-苯并[D]咪唑三盐酸盐、MCOPPB(盐酸盐)、化合物MCOPPB TRIHYDROCHLRIDE

MCOPPB三盐酸盐（CAS 1108147-88-1）是晶世纪化学数据库收录的有机酸。分子式为 C26H43Cl3N4，分子量为 518.005 g/mol。又称 1-[1-(1-甲基环辛基)-4-哌啶基]-2-[(3R)-3-哌啶基]-1H-苯并咪唑三盐酸盐、1-(1-(1-甲基环辛基)哌啶-4-基)-2-(哌啶-3-基)-1H-苯并[D]咪唑三盐酸盐、MCOPPB(盐酸盐)。目前暂无供应商报价，可通过联系页询价。数据更新于 2026年8月21日。

CAS号: 1108147-88-1
晶世纪编号: J-998098-3
分子式: C₂₆H₄₃Cl₃N₄
分子量: 518.005 g/mol
分类: 有机酸
更新时间: 2026/8/21

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基础理化性质

精确质量	516.255310
其他信息	33.09000
LogP	8.31590
储存条件	2-8℃

活性 / 生物活性

相关类别	信号通路 >> G 蛋白偶联受体/G 蛋白 >> 阿片受体信号通路 >> 神经信号通路 >> 阿片受体研究领域 >> 其他
参考文献	[1]. Hayashi, Shigeo; Hirao, Akiko; Imai, Aki; Nakamura, Hiroshi; Murata, Yoshinori; Ohashi, Katsuyo; Nakata, Eriko. Novel Non-Peptide Nociceptin/Orphanin FQ Receptor Agonist, 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole: Design, Synthesis, and Structure-Activity Relationship of Oral Receptor Occupancy in the Brain for Orally Potent Antianxiety Drug. Journal of Medicinal Chemistry (2009), 52(3), 610-625. [2]. Hayashi S, Hirao A, Imai A, Nakamura H, Murata Y, Ohashi K, Nakata E.Novel non-peptide nociceptin/orphanin FQ receptor agonist, 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole: design, synthesis, and structure-activity relationship of oral receptor occupancy in the brain for orally potent antianxiety drug.J Med Chem. 2009 Feb 12;52(3):610-25. [3]. Hirao A, Imai A, Sugie Y, Yamada Y, Hayashi S, Toide K.Pharmacological characterization of the newly synthesized nociceptin/orphanin FQ-receptor agonist 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole as an anxiolytic agent.J Pharmacol Sci. 2008 Mar;106(3):361-8. Epub 2008 Mar 5.

相关类别

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 阿片受体信号通路 >> 神经信号通路 >> 阿片受体研究领域 >> 其他

参考文献

[1]. Hayashi, Shigeo; Hirao, Akiko; Imai, Aki; Nakamura, Hiroshi; Murata, Yoshinori; Ohashi, Katsuyo; Nakata, Eriko. Novel Non-Peptide Nociceptin/Orphanin FQ Receptor Agonist, 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole: Design, Synthesis, and Structure-Activity Relationship of Oral Receptor Occupancy in the Brain for Orally Potent Antianxiety Drug. Journal of Medicinal Chemistry (2009), 52(3), 610-625. [2]. Hayashi S, Hirao A, Imai A, Nakamura H, Murata Y, Ohashi K, Nakata E.Novel non-peptide nociceptin/orphanin FQ receptor agonist, 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole: design, synthesis, and structure-activity relationship of oral receptor occupancy in the brain for orally potent antianxiety drug.J Med Chem. 2009 Feb 12;52(3):610-25. [3]. Hirao A, Imai A, Sugie Y, Yamada Y, Hayashi S, Toide K.Pharmacological characterization of the newly synthesized nociceptin/orphanin FQ-receptor agonist 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole as an anxiolytic agent.J Pharmacol Sci. 2008 Mar;106(3):361-8. Epub 2008 Mar 5.

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