盐酸伐尼克兰

别名 / 同义词: 6,7,8,9-四氢-6,10-甲桥-6H-吡嗪并[2,3-h][3]苯并氮杂卓盐酸盐、7,8,9,10-四氢-6H-6,10-甲桥氮杂卓[4,5-g]喹喔啉盐酸盐、伐仑克林、化合物 T23502、盐酸伐仑克林、盐酸伐伦克林

盐酸伐尼克兰（CAS 230615-23-3）是晶世纪化学数据库收录的有机酸。分子式为 C13H14ClN3，分子量为 247.723 g/mol。又称 6,7,8,9-四氢-6,10-甲桥-6H-吡嗪并[2,3-h][3]苯并氮杂卓盐酸盐、7,8,9,10-四氢-6H-6,10-甲桥氮杂卓[4,5-g]喹喔啉盐酸盐、伐仑克林。目前暂无供应商报价，可通过联系页询价。数据更新于 2026年8月21日。

CAS号: 230615-23-3
晶世纪编号: J-1982858-1
分子式: C₁₃H₁₄ClN₃
分子量: 247.723 g/mol
分类: 有机酸
更新时间: 2026/8/21

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基础理化性质

精确质量	247.087631
其他信息	37.81000
LogP	2.93470
储存条件	2-8℃

活性 / 生物活性

相关类别	信号通路 >> 跨膜转运 >> 胆碱受体信号通路 >> 神经信号通路 >> 胆碱受体研究领域 >> 神经疾病
参考文献	[1]. Kikkawa, H.; Maruyama, N.; Fujimoto, Y.; Hasunuma, T. Single- and multiple-dose pharmacokinetics of the selective nicotinic receptor partial agonist, varenicline, in healthy Japanese adult smokers. Journal of Clinical Pharmacology (2011), 51(4), 527-537. [2]. Krebs P, Sherman SE. Review: Varenicline for tobacco cessation does not increase CV serious adverse events. Ann Intern Med. 2012 Aug 21;157(4):JC2-2. [3]. Pachas GN, Cather C, Pratt SA et al. Varenicline for Smoking Cessation in Schizophrenia: Safety and Effectiveness in a 12-Week, Open-Label Trial. J Dual Diagn. 2012;8(2):117-125. [4]. Bordia T, Hrachova M, Chin M et al. Varenicline Is a Potent Partial Agonist at α6β2* Nicotinic Acetylcholine Receptors in Rat and Monkey Striatum. J Pharmacol Exp Ther. 2012 Aug;342(2):327-34.

相关类别

信号通路 >> 跨膜转运 >> 胆碱受体信号通路 >> 神经信号通路 >> 胆碱受体研究领域 >> 神经疾病

参考文献

[1]. Kikkawa, H.; Maruyama, N.; Fujimoto, Y.; Hasunuma, T. Single- and multiple-dose pharmacokinetics of the selective nicotinic receptor partial agonist, varenicline, in healthy Japanese adult smokers. Journal of Clinical Pharmacology (2011), 51(4), 527-537. [2]. Krebs P, Sherman SE. Review: Varenicline for tobacco cessation does not increase CV serious adverse events. Ann Intern Med. 2012 Aug 21;157(4):JC2-2. [3]. Pachas GN, Cather C, Pratt SA et al. Varenicline for Smoking Cessation in Schizophrenia: Safety and Effectiveness in a 12-Week, Open-Label Trial. J Dual Diagn. 2012;8(2):117-125. [4]. Bordia T, Hrachova M, Chin M et al. Varenicline Is a Potent Partial Agonist at α6β2* Nicotinic Acetylcholine Receptors in Rat and Monkey Striatum. J Pharmacol Exp Ther. 2012 Aug;342(2):327-34.

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