盐酸昂丹司琼

别名 / 同义词: 盐酸恩丹西酮、盐酸枢复宁、帕罗西汀EP杂质A、帕罗西汀杂质A、盐酸蒽丹西酮、昂丹司琼盐酸盐

该化合物暂无报价。

基础理化性质

描述	Ondansetron盐酸盐是5-HT3受体拮抗剂,可作为化疗后止吐剂。
相关类别	信号通路 >> G 蛋白偶联受体/G 蛋白 >> 5-HT受体信号通路 >> 神经信号通路 >> 5-HT受体研究领域 >> 神经疾病
参考文献	[1]. Brown AM, et al. Ion permeation and conduction in a human recombinant 5-HT3 receptor subunit (h5-HT3A). J Physiol. 1998 Mar 15;507 ( Pt 3):653-65. [2]. Barann M, et al. Recombinant human 5-HT3A receptors in outside-out patches of HEK 293 cells: basic properties and barbiturate effects. Naunyn Schmiedebergs Arch Pharmacol. 2000 Sep;362(3):255-65. [3]. Wildeboer KM, et al. Ondansetron results in improved auditory gating in DBA/2 mice through a cholinergic mechanism. Brain Res. 2009 Dec 1;1300:41-50. [4]. Khedhaier A, et al. Circadian rhythms in toxic effects of the serotonin antagonist ondansetron in mice. Chronobiol Int. 2003 Nov;20(6):1103-16. [5]. Umathe SN, et al. The 5-HT3 receptor antagonist, ondansetron, blocks the development and expression of ethanol-induced locomotor sensitization in mice. Behav Pharmacol. 2009 Feb;20(1):78-83. [6]. Doggrell SA, et al. Cardiac safety concerns for ondansetron, an antiemetic commonly used for nausea linked to cancer treatment and following anaesthesia. Expert Opin Drug Saf. 2013 May;12(3):421-31.

盐酸昂丹司琼的 CAS 号是多少？

99614-01-4

盐酸昂丹司琼的分子式和分子量是什么？

C18H20ClN3O，分子量 329.824 g/mol

盐酸昂丹司琼的上游和下游产品有哪些？

上游产品: 昂丹司琼、1,2,3,9-四氢-9-甲基咔唑酮、四甲基甲烷二胺；下游产品: 昂丹司琼

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