AR-42

别名 / 同义词: (S)-(+)-N-羟基-4-(3-甲基-2-苯基丁酰氨基)苯甲酰胺、(S)-N-羟基-4-(3-甲基-2-苯基丁酰胺基)苯甲酰胺、AR-42,HDAC抑制剂、化合物AR42、化合物AR42,10 MM DMSO 溶液

AR-42（CAS 935881-37-1）是晶世纪化学数据库收录的有机化合物。分子式为 C18H20N2O3，分子量为 312.36300 g/mol。又称 (S)-(+)-N-羟基-4-(3-甲基-2-苯基丁酰氨基)苯甲酰胺、(S)-N-羟基-4-(3-甲基-2-苯基丁酰胺基)苯甲酰胺、AR-42,HDAC抑制剂。主要理化性质包括密度 1.223。目前暂无供应商报价，可通过联系页询价。数据更新于 2026年8月21日。

CAS号: 935881-37-1
晶世纪编号: J-1957179-9
分子式: C₁₈H₂₀N₂O₃
分子量: 312.36300 g/mol
分类: 有机化合物
更新时间: 2026/8/21

该化合物暂无报价。

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基础理化性质

密度	1.223
精确质量	312.14700
其他信息	78.43000
LogP	3.64780
外观性状	粉末
储存条件	-20℃

活性 / 生物活性

相关类别	研究领域 >> 癌症
参考文献	[1]. Lu YS, Chou CH, Tzen KY, Gao M, Cheng AL, Kulp SK, Cheng JC.Radiosensitizing effect of a phenylbutyrate-derived histone deacetylase inhibitor in hepatocellular carcinoma.Int J Radiat Oncol Biol Phys. 2012 Jun 1;83(2):e181-9. Epub 2012 Feb 28. [2]. Zimmerman B, Sargeant A, Landes K, Fernandez SA, Chen CS, Lairmore MD.Efficacy of novel histone deacetylase inhibitor, AR42, in a mouse model of, human T-lymphotropic virus type 1 adult T cell lymphoma.Leuk Res. 2011 Nov;35(11):1491-7. Epub 2011 Jul 29. [3]. Zhang S, Suvannasankha A, Crean CD, White VL, Chen CS, Farag SS.The novel histone deacetylase inhibitor, AR-42, inhibits gp130/Stat3 pathway and induces apoptosis and cell cycle arrest in multiple myeloma cells.Int J Cancer. 2011 Jul 1;129(1):204-13. [4]. Lin TY et al. AR-42, a novel HDAC inhibitor, exhibits biologic activity against malignant mast cell lines via down-regulation of constitutively activated Kit. Blood. 2010 May 27;115(21):4217-25. [5]. Shuhong Zhang et al. The novel histone deacetylase inhibitor, AR-42, inhibits gp130/Stat3 pathway and induces apoptosis and cell cycle arrest in multiple myeloma cells International Journal of Cancer Volume 129, Issue 1, pages 204-213, 1 July 2011

相关类别

研究领域 >> 癌症

参考文献

[1]. Lu YS, Chou CH, Tzen KY, Gao M, Cheng AL, Kulp SK, Cheng JC.Radiosensitizing effect of a phenylbutyrate-derived histone deacetylase inhibitor in hepatocellular carcinoma.Int J Radiat Oncol Biol Phys. 2012 Jun 1;83(2):e181-9. Epub 2012 Feb 28. [2]. Zimmerman B, Sargeant A, Landes K, Fernandez SA, Chen CS, Lairmore MD.Efficacy of novel histone deacetylase inhibitor, AR42, in a mouse model of, human T-lymphotropic virus type 1 adult T cell lymphoma.Leuk Res. 2011 Nov;35(11):1491-7. Epub 2011 Jul 29. [3]. Zhang S, Suvannasankha A, Crean CD, White VL, Chen CS, Farag SS.The novel histone deacetylase inhibitor, AR-42, inhibits gp130/Stat3 pathway and induces apoptosis and cell cycle arrest in multiple myeloma cells.Int J Cancer. 2011 Jul 1;129(1):204-13. [4]. Lin TY et al. AR-42, a novel HDAC inhibitor, exhibits biologic activity against malignant mast cell lines via down-regulation of constitutively activated Kit. Blood. 2010 May 27;115(21):4217-25. [5]. Shuhong Zhang et al. The novel histone deacetylase inhibitor, AR-42, inhibits gp130/Stat3 pathway and induces apoptosis and cell cycle arrest in multiple myeloma cells International Journal of Cancer Volume 129, Issue 1, pages 204-213, 1 July 2011

海关 / 贸易信息

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

常见问题

AR-42 的 CAS 号是多少？

AR-42 的 CAS 号是 935881-37-1。

AR-42 的分子式和分子量是什么？

AR-42 的分子式为 C18H20N2O3，分子量为 312.36300 g/mol。

数据来自公开化学数据库与供应商目录；供应商报价由供应商提供。

更新时间: 2026/8/21

引用格式: 晶世纪. “AR-42 (CAS 935881-37-1)”. 晶世纪化学数据库. https://www.jingsj.com/zh/compound/J-1957179-9（访问日期：2026-10-27）。

数据仅供参考；采购前请与供应商核实规格、等级与法规状态。