[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"currency-rates":3,"$fyk2oeqxpb7bd":8,"compound-J-49199-6":169,"verified-suppliers-J-49199-6":360},{"rates":4,"source":7},{"USD":5,"CNY":6},1,6.679814,"live",{"rows":9,"total":167,"current":5,"size":168},[10,33,45,60,73,84,96,111,121,133,145,156],{"slug":11,"cid":12,"imgSvg":13,"name":14,"nameZh":15,"cas":16,"formula":17,"iupac":14,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":22,"offersCount":24,"supplierCount":25,"bestOffer":26},"843627791009189888","J-1971488-6","\u002Fimages\u002Fchem_structures_svg\u002F399\u002F65845-61-6.svg","N-Methylcyclohexanamine hydrochloride","N-甲基环己胺盐酸盐","65845-61-6","C7H16ClN","acids","有机酸","Organic Acids","",[23],"In Stock",4,2,{"unitPrice":27,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},2.64,"500g","CNY","China","CN","in-stock",{"slug":34,"cid":35,"imgSvg":36,"name":37,"nameZh":38,"cas":39,"formula":40,"iupac":37,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":41,"offersCount":24,"supplierCount":5,"bestOffer":42},"785882541994283008","J-1323843-2","\u002Fimages\u002Fchem_structures_svg\u002F104\u002F67627-18-3.svg","Potassium indigotrisulfonate","靛蓝三磺酸钾","67627-18-3","C16H7K3N2O11S3",[23],{"unitPrice":43,"pack":44,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},180,"5g",{"slug":46,"cid":47,"imgSvg":48,"name":49,"nameZh":50,"cas":51,"formula":52,"iupac":49,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":56,"offersCount":57,"supplierCount":25,"bestOffer":58},"785889752443260928","J-28559-6","\u002Fimages\u002Fchem_structures_svg\u002F292\u002F15060-55-6.svg","Ammonium tetrathiomolybdate","四硫钼酸铵","15060-55-6","H8MoN2S4","inorganic","无机化合物","Inorganic Chemicals",[23],10,{"unitPrice":59,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},24,{"slug":61,"cid":62,"imgSvg":63,"name":64,"nameZh":65,"cas":66,"formula":67,"iupac":64,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":68,"offersCount":69,"supplierCount":25,"bestOffer":70},"855452191530422272","J-1994428-6","\u002Fimages\u002Fchem_structures_svg\u002F500\u002F16350-96-2.svg","N-benzylcyclohexanamine.hydrochloride","N-苄基环己胺盐酸盐","16350-96-2","C13H20ClN",[23],5,{"unitPrice":71,"pack":28,"currency":29,"origin":72,"originFlag":31,"moq":21,"stock":32},6,"中国",{"slug":74,"cid":75,"imgSvg":76,"name":77,"nameZh":78,"cas":79,"formula":80,"iupac":77,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":81,"offersCount":25,"supplierCount":25,"bestOffer":82},"785871840001134592","J-982001-3","\u002Fimages\u002Fchem_structures_svg\u002F001\u002F10517-44-9.svg","1,3-Diaminopropane dihydrochloride","1,3-二氨基丙烷二盐酸盐","10517-44-9","C3H12Cl2N2",[23],{"unitPrice":83,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},3.78,{"slug":85,"cid":86,"imgSvg":87,"name":88,"nameZh":89,"cas":90,"formula":91,"iupac":88,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":92,"offersCount":93,"supplierCount":94,"bestOffer":95},"785880365658017792","J-14975-7","\u002Fimages\u002Fchem_structures_svg\u002F262\u002F12003-67-7.svg","Lithium aluminate","氧化铝锂","12003-67-7","AlLiO2",[23],7,3,{"unitPrice":94,"pack":28,"currency":29,"origin":72,"originFlag":31,"moq":21,"stock":32},{"slug":97,"cid":98,"imgSvg":99,"name":100,"nameZh":101,"cas":102,"formula":103,"iupac":100,"category":104,"categoryName":105,"categoryEnName":106,"industry":21,"tags":107,"offersCount":94,"supplierCount":5,"bestOffer":109},"785871830249377792","J-6931-8","\u002Fimages\u002Fchem_structures_svg\u002F456\u002F58068-80-7.svg","1-Octanoylbenzotriazole","N-辛酰苯并三唑","58068-80-7","C14H19N3O","aromatics","芳香烃","Aromatic Hydrocarbons",[108],"Made to Order",{"unitPrice":110,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},0.56,{"slug":112,"cid":113,"imgSvg":114,"name":115,"nameZh":116,"cas":117,"formula":118,"iupac":115,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":119,"offersCount":69,"supplierCount":25,"bestOffer":120},"785871842446413824","J-1960944-0","\u002Fimages\u002Fchem_structures_svg\u002F495\u002F10534-86-8.svg","Hexaamminecobalt(III) nitrate","六氨合钴(III)硝酸盐","10534-86-8","CoH18N9O9",[23],{"unitPrice":71,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},{"slug":122,"cid":123,"imgSvg":124,"name":125,"nameZh":126,"cas":127,"formula":128,"iupac":125,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":129,"offersCount":24,"supplierCount":25,"bestOffer":130},"785871842576437248","J-814544-6","\u002Fimages\u002Fchem_structures_svg\u002F221\u002F12037-42-2.svg","vanadium oxide","氧化钒","12037-42-2","O13V6",[23],{"unitPrice":131,"pack":132,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},112.8,"100g",{"slug":134,"cid":135,"imgSvg":136,"name":137,"nameZh":138,"cas":139,"formula":140,"iupac":137,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":141,"offersCount":142,"supplierCount":5,"bestOffer":143},"785871842647740416","J-1333345-4","\u002Fimages\u002Fchem_structures_svg\u002F479\u002F26490-63-1.svg","COBALT TETRAFLUOROBORATE HEXAHYDRATE","四氟化硼钴水合物","26490-63-1","B2CoF8H12O6",[23],8,{"unitPrice":144,"pack":132,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},11,{"slug":146,"cid":147,"imgSvg":148,"name":149,"nameZh":150,"cas":151,"formula":152,"iupac":149,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":153,"offersCount":57,"supplierCount":94,"bestOffer":154},"785871842698072064","J-814953-9","\u002Fimages\u002Fchem_structures_svg\u002F432\u002F72259-10-0.svg","Copper(II) tetrafluoroborate hexahydrate","六水合四氟硼酸铜(II)","72259-10-0","B2CuF8H12O6",[23],{"unitPrice":155,"pack":28,"currency":29,"origin":21,"originFlag":21,"moq":21,"stock":32},2.6,{"slug":157,"cid":158,"imgSvg":159,"name":160,"nameZh":161,"cas":162,"formula":163,"iupac":160,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":164,"offersCount":94,"supplierCount":5,"bestOffer":165},"785871863254355968","J-1990080-2","\u002Fimages\u002Fchem_structures_svg\u002F149\u002F123333-60-8.svg","Cerium(IV) sulfate hydrate","铈(IV)硫酸盐水合物","123333-60-8","CeH2O9S2",[108],{"unitPrice":166,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},5.6,3204,12,{"slug":170,"cid":171,"imgSvg":172,"name":173,"nameZh":174,"cas":175,"formula":176,"iupac":173,"mdl":21,"mw":177,"category":178,"categoryName":179,"categoryEnName":180,"industry":21,"tags":181,"synonyms":182,"properties":186,"ghs":237,"offers":238,"activity":239,"upstream":249,"downstream":268,"customs":281,"safetyRows":282,"toxicity":283,"synthesis":284,"updatedAt":285,"isProhibited":286,"related":287,"__ts":358,"__lang":359,"__slug":171},"785898089499070464","J-49199-6","\u002Fimages\u002Fchem_structures_svg\u002F282\u002F81840-15-5.svg","Vesnarinone","维司力农","81840-15-5","C22H25N3O4","395.45200","organic","有机化合物","Organic Compounds",[],[183,184,185],"威那利酮","3,4-二氢-6-[4-(3,4-二甲氧苯甲酰)-1-哌嗪基]-2(1H)-喹啉酮","6-(4-(3,4-二甲氧基苯甲酰基)哌嗪-1-基)-3,4-二氢喹啉-2(1H)-酮",[187,192,197,202,207,211,214,217,221,225,229,233],{"label":188,"labelZh":189,"value":190,"prop":191},"Melting Point","熔点","238.1-239.5° (Tominaga); mp 238.1-239.8° (Shimizu)","meltingPoint",{"label":193,"labelZh":194,"value":195,"prop":196},"Boiling Point","沸点","678.3ºC at 760 mmHg","boilingPoint",{"label":198,"labelZh":199,"value":200,"prop":201},"Density","密度","1.246g\u002Fcm3","density",{"label":203,"labelZh":204,"value":205,"prop":206},"Flash Point","闪点","364ºC","flashPoint",{"label":208,"labelZh":209,"value":210},"Exact Mass","精确质量","395.18500",{"label":212,"labelZh":212,"value":213},"PSA","71.11000",{"label":215,"labelZh":215,"value":216},"LogP","2.69180",{"label":218,"labelZh":219,"value":220},"Refractive Index","折射率","1.601",{"label":222,"labelZh":223,"value":224},"Storage Conditions","储存条件","2-8℃",{"label":226,"labelZh":227,"value":228},"Molecular Structure","分子结构","1、 摩尔折射率：108.67\n2、 摩尔体积（cm\n3\n\u002Fmol）：317.1\n3、 等张比容（90.2K）：843.9\n4、 表面张力（dyne\u002Fcm）：50.1\n5、 极化率（10-24cm3）：43.08",{"label":230,"labelZh":231,"value":232},"Computational Chemistry","计算化学","1.疏水参数计算参考值（XlogP）:2.1\n2.氢键供体数量:1\n3.氢键受体数量:5\n4.可旋转化学键数量:4\n5.互变异构体数量:3\n6.拓扑分子极性表面积71.1\n7.重原子数量:29\n8.表面电荷:0\n9.复杂度:593\n10.同位素原子数量:0\n11.确定原子立构中心数量:0\n12.不确定原子立构中心数量:0\n13.确定化学键立构中心数量:0\n14.不确定化学键立构中心数量:0\n15.共价键单元数量:1",{"label":234,"labelZh":235,"value":236},"Additional Property","更多","1.性状：从乙醇-氯仿得无色颗粒状结晶。\n2.熔点238.1-239.5℃.也有无臭无味的淡黄色结晶性粉末,熔点238.1-239.8℃.\n3.UV最大吸收(甲醇，乙醇，氯仿)：271nm(ε25100，25200，23000，C=10μg\u002Fm1)。\n4.溶解度%(25℃)：冰醋酸18.68,氯仿14.19,苄醇5.913,N-甲基-2-吡咯啉酮3.407,二甲亚砜2.509,环丁砜1.229,二甲基甲酰胺1.179,二氧六环0.1653,甲醇0.1151,丙酮0.06389,乙醇0.04005,水0.002086。\n5.pKa 2.86。",null,[],[240,243,246],{"key":241,"value":242},"描述","Vesnarinone是一种喹啉酮衍生物, 药效学效应包括抑制磷酸二酯酶III (PDE3) 活性,增加钙通量, 及减小钾通量。",{"key":244,"value":245},"相关类别","信号通路\n>>\n代谢酶\u002F蛋白酶\n>>\n磷酸二酯酶(PDE)\n研究领域\n>>\n感染",{"key":247,"value":248},"参考文献","[1].\nKatayama Y, et al. Inhibitory effects of Vesnarinone on cloned cardiac delayed rectifier K(+) channels expressed in a mammalian cell line. J Pharmacol Exp Ther. 2000 Jul;294(1):339-46.\n[2].\nInage M, et al. Vesnarinone represses the fibrotic changes in murine lung injury induced by bleomycin. Int J Biol Sci. 2009;5(4):304-10.\n[3].\nCavusoglu E, et al. Vesnarinone: a new inotropic agent for treating congestive heart failure. J Card Fail. 1995 Jun;1(3):249-57.\n[4].\nMatsumori A, et al. Vesnarinone, a new inotropic agent, inhibits cytokine production by stimulated human blood from patients with heart failure. Circulation. 1994 Mar;89(3):955-8.",[250,256,262],{"slug":251,"cid":252,"name":253,"nameZh":253,"cas":254,"imgSvg":255},"785895691720331300","J-1511049-3","6-氨基-3,4-二氢-2(1...","22246-13-5","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F211\u002F22246-13-5.svg",{"slug":257,"cid":258,"name":259,"nameZh":259,"cas":260,"imgSvg":261},"785896971708665900","J-45955-2","3,4-二甲氧基苯甲酰氯","3535-37-3","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F207\u002F3535-37-3.svg",{"slug":263,"cid":264,"name":265,"nameZh":265,"cas":266,"imgSvg":267},"785893938648059900","J-1499706-9","双(2-溴乙基)胺氢溴酸盐","43204-63-3","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F461\u002F43204-63-3.svg",[269,275],{"slug":270,"cid":271,"name":272,"nameZh":272,"cas":273,"imgSvg":274},"785891823926120400","J-31220-9","3,4-二甲氧基苯甲酸乙酯","3943-77-9","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F004\u002F3943-77-9.svg",{"slug":276,"cid":277,"name":278,"nameZh":278,"cas":279,"imgSvg":280},"785897816030449700","J-48026-2","藜芦酸","93-07-2","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F179\u002F93-07-2.svg",[],[],"\u003Ctd>\n\n\u003Cp>\u003Ca href=\"\u002Fen\u002Fcas\u002F81840-15-5_1193291.html#duXinDiv\">维司力农毒性英文版\u003C\u002Fa>\u003C\u002Fp>\n\n\u003C\u002Ftd>","\u003Cp> 以6-氨基-3，4-二氢-2(1H)-喹啉酮为原料。将6-氨基-3，4-二氢-2(1H)-喹啉酮(21.1g，0.13mo1)和双(伊溴乙基)胺氢溴酸盐(40.5g，0.13mo1)溶于150ml乙醇，回流搅拌8h。冷却，加入碳酸钠(13.8g，0.13mo1)，再回流搅拌8h。冷至室温，过滤收集析出的沉淀，用乙醇洗，乙醇-水重结晶，得26.4g无色针状结晶的3，4-二氢-6-(1-哌嗪基)-2(1H)-喹啉酮氢溴酸盐，收率64%，熔点289--293℃(分解)。\u003Cbr \u002F>将上述得到的喹啉酮衍生物(3.1g，0.010mo1)和三乙胺(2.2g，0.022mo1)溶于40ml无水二甲基甲酰胺，在冰浴冷却和搅拌下，滴加3，4-二甲氧苯甲酰氯(2.2g，0.0l 1mo1)在10ml无水二甲基甲酰胺中的溶液。加毕，在室温下搅拌1h。将反应液倾入冰水，用氯仿提取。提取液水洗，无水硫酸钠干燥，减压浓缩。剩余物用硅胶层析，氯仿-甲醇(100：1)洗脱。然后再用乙醇-氯仿重结晶，得2.7g无色颗粒状结晶的维司力农，收率70%，熔点238～239.5℃。 \u003C\u002Fp>","2026-08-21T07:51:12.859463Z",false,[288,294,299,305,311,317,323,329,334,340,346,352],{"slug":289,"cid":290,"name":291,"nameZh":292,"cas":293},"785882572553981952","J-1110759-8","Methyl Violet 2B","甲基紫2B","8004-87-3",{"slug":295,"cid":296,"name":297,"nameZh":297,"cas":298},"785911446427930624","J-69315-2","9-Bromo-10-(naphthalen-1-yl-d7)anthracene-1,2,3,4,5,6,7,8-d8","2330770-73-3",{"slug":300,"cid":301,"name":302,"nameZh":303,"cas":304},"785893849972084736","J-1499066-0","Ferrocholinate","铁胆盐","1336-80-7",{"slug":306,"cid":307,"name":308,"nameZh":309,"cas":310},"785872510607429632","J-1334045-9","calcium saccharin","糖精钙","6485-34-3",{"slug":312,"cid":313,"name":314,"nameZh":315,"cas":316},"785898743068102656","J-1365189-3","Esomeprazole calcium","埃索美拉唑钙","161796-85-6",{"slug":318,"cid":319,"name":320,"nameZh":321,"cas":322},"785884051318771712","J-1114131-4","Alizarin Complexone","茜素络合指示剂","3952-78-1",{"slug":324,"cid":325,"name":326,"nameZh":327,"cas":328},"785896769497075712","J-45303-2","Cholecalciferol","维生素D3","67-97-0",{"slug":330,"cid":331,"name":332,"nameZh":332,"cas":333},"785914490636996608","J-1241469-6","2-Chloro-4-(1-dibenzofuranyl)-6-(1-naphthalenyl)-1,3,5-triazine","2417986-80-0",{"slug":335,"cid":336,"name":337,"nameZh":338,"cas":339},"785871874079854592","J-1110697-1","Crystal Violet","结晶紫","548-62-9",{"slug":341,"cid":342,"name":343,"nameZh":344,"cas":345},"785895040399446016","J-1110640-4","Solvent Red 27","溶剂红27","1320-06-5",{"slug":347,"cid":348,"name":349,"nameZh":350,"cas":351},"785888480654790656","J-1958131-8","Rabeprazole sodium","雷贝拉唑钠","117976-90-6",{"slug":353,"cid":354,"name":355,"nameZh":356,"cas":357},"785897800498941952","J-47960-7","Solvent Red 24","苏丹Ⅳ","85-83-6",1794255302571,"zh-CN",[]]