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GHS08",{"key":370,"value":257},"信号词",{"key":372,"value":373},"危害声明","H302-H350",{"key":375,"value":376},"警示性声明","P201-P308 + P313",{"key":378,"value":379},"个人防护装备","Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges",{"key":381,"value":382},"危害码 (欧洲)","T:Toxic",{"key":384,"value":385},"风险声明 (欧洲)","R22;R45",{"key":387,"value":388},"安全声明 (欧洲)","S53-S45",{"key":390,"value":391},"危险品运输编码","1230.0",{"key":393,"value":394},"WGK德国","3",{"key":396,"value":397},"RTECS号","AM4375000",{"key":363,"value":364},"\u003Ctd>\n\n\u003Cp>\u003Ca href=\"\u002Fen\u002Fcas\u002F62-44-2_895613.html#duXinDiv\">非那西丁毒性英文版\u003C\u002Fa>\u003C\u002Fp>\n\n\u003C\u002Ftd>","\u003Cp>(1)由对氨基苯乙醚经乙酰化而得。将苯、乙酐和对氨基苯乙醚的混合物，在油浴上加热共沸4h，反应完毕后冷却反应物，即析出非那汀，经过滤，冷苯洗涤，干燥即得，产量为理论量的86%。  \u003C\u002Fp>\u003Cp>(2)由乙酰氨基苯酚与乙醇钠作用而得：先将对乙酰胺基苯酚加于乙醇钠中，再缓缓加入碘乙烷，加热回流1h，冷却，过滤，所得粗品溶于乙醇中，过滤，滤液用热水稀释，再经冷却,过滤，干燥，而得成品，产量为理论量的80%。第一个方法也可不用苯作溶剂，而用乙酸代替，工艺过程如下。将40%的稀乙酸加热至沸，投入对氨基苯乙醚，蒸去水，待温度升到150℃时加入冰醋酸，回流1h，继续蒸，待温度升至150℃以上，取样测定游离氨基苯乙醚，根据残余的氨基苯乙醚量加入乙酐，回流反应0.5h，检查终点，合格后减压，回收乙酸至氨基含量在0.046以下，含酸0.2%以下，将反应液压入热精制母液中，搅拌降温至40℃，过滤，得非那西汀粗品。精制，非那西汀粗品加沸水或精制母液，加热搅拌溶解，过滤，滤液用酸调节至pH=4.5-4.7，加入活性炭及硫代硫酸钠搅拌脱色，过滤，滤液冷却结晶，甩滤，气流干燥，得非那西汀。 \u003C\u002Fp>","\u003Ctd>\n\r\n                                        \r\n                                        非那西丁\n\u003Cb>修改号码：6\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块1. 化学品\u003C\u002Fstrong>\n\u003Cbr \u002F> 产品名称：\n\u003Cb>Phenacetin\u003C\u002Fb>\n\u003Cbr \u002F> 修改号码：\n\u003Cb>6\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块2. 危险性概述\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>GHS分类\u003C\u002Fb>\n\u003Cbr \u002F> 　物理性危害未分类\n\u003Cbr \u002F> 　健康危害\n\u003Cbr \u002F> 急性毒性（经口）\n\u003Cb>第4级\u003C\u002Fb>\n\u003Cbr \u002F> 生殖细胞敏感性\n\u003Cb>第2级\u003C\u002Fb>\n\u003Cbr \u002F> 致癌性\n\u003Cb>1A类\u003C\u002Fb>\n\u003Cbr \u002F> 生殖毒性（对哺乳影响或通过哺乳影响）对哺乳影响或通过哺乳影响的追加分类\n\u003Cbr \u002F> 特异性靶器官毒性中枢神经系统\n\u003Cbr \u002F>\n\u003Cb>- 单一接触 [第1级]\u003C\u002Fb>\n\u003Cbr \u002F> 特异性靶器官毒性\n\u003Cb>血液, 肾脏\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>- 单一接触 [第1级]\u003C\u002Fb>\n\u003Cbr \u002F> 　环境危害未分类\n\u003Cbr \u002F>\n\u003Cb>GHS标签元素\u003C\u002Fb>\n\u003Cbr \u002F> 　图标或危害标志\n\u003Cbr \u002F> 　信号词危险\n\u003Cbr \u002F> 　危险描述吞咽有害。\n\u003Cbr \u002F> 怀疑会造成遗传缺陷\n\u003Cbr \u002F> 可能致癌\n\u003Cbr \u002F> 可能对母乳喂养的孩子造成损害\n\u003Cbr \u002F> 对器官引起损害： 中枢神经系统\n\u003Cbr \u002F> 可能因延长或接触对器官产生损害： 血液 肾脏\n\u003Cbr \u002F> 　防范说明\n\u003Cbr \u002F> 非那西丁\n\u003Cb>修改号码：6\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块2. 危险性概述\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>[预防]\u003C\u002Fb>使用前获取特定手册。\n\u003Cbr \u002F> 处理前必须阅读并理解所有安全措施。\n\u003Cbr \u002F> 切勿吸入。\n\u003Cbr \u002F>\n\u003Cb>在怀孕\u002F哺乳期间避免接触。\u003C\u002Fb>\n\u003Cbr \u002F> 使用本产品时切勿吃东西，喝水或吸烟。\n\u003Cbr \u002F> 处理后要彻底清洗双手。\n\u003Cbr \u002F> 使用个人所需的防护用具。\n\u003Cbr \u002F>\n\u003Cb>[急救措施]\u003C\u002Fb>\n\u003Cb>食入：若感不适，呼叫解毒中心\u002F医生。漱口。\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>如接触到或相关接触：求医\u002F就诊。\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>[储存]\u003C\u002Fb>存放处须加锁。\n\u003Cbr \u002F>\n\u003Cb>[废弃处置]\u003C\u002Fb>\n\u003Cb>根据当地政府规定把物品\u002F容器交与工业废弃处理机构。\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块3. 成分\u002F组成信息\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>单一物质\u002F混和物\u003C\u002Fb>单一物质\n\u003Cbr \u002F>\n\u003Cb>化学名(中文名)：\u003C\u002Fb>非那西丁\n\u003Cbr \u002F> 百分比：\n\u003Cb>>99.0%(GC)\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>CAS编码：\u003C\u002Fb>\n\u003Cb>62-44-2\u003C\u002Fb>\n\u003Cbr \u002F> 俗名：\n\u003Cb>N-Acetyl-4-ethoxyaniline , N-Acetyl-p-phenetidine , 4'-Ethoxyacetanilide\u003C\u002Fb>\n\u003Cbr \u002F> 分子式：\n\u003Cb>C10H13NO2\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块4. 急救措施\u003C\u002Fstrong>\n\u003Cbr \u002F> 吸入：\n\u003Cb>将受害者移到新鲜空气处，保持呼吸通畅，休息。求医\u002F就诊。\u003C\u002Fb>\n\u003Cbr \u002F> 皮肤接触：\n\u003Cb>立即去除\u002F脱掉所有被污染的衣物。用大量肥皂和水轻轻洗。\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>求医\u002F就诊。\u003C\u002Fb>\n\u003Cbr \u002F> 眼睛接触：用水小心清洗几分钟。如果方便，易操作，摘除隐形眼镜。\n\u003Cbr \u002F>\n\u003Cb>求医\u002F就诊。\u003C\u002Fb>\n\u003Cbr \u002F> 食入：\n\u003Cb>求医\u002F就诊。漱口。\u003C\u002Fb>\n\u003Cbr \u002F> 紧急救助者的防护：救援者需要穿戴个人防护用品，比如橡胶手套和气密性护目镜。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块5. 消防措施\u003C\u002Fstrong>\n\u003Cbr \u002F> 合适的灭火剂：干粉，泡沫，雾状水，二氧化碳\n\u003Cbr \u002F> 特殊危险性：小心，燃烧或高温下可能分解产生毒烟。\n\u003Cbr \u002F> 特定方法：从上风处灭火，根据周围环境选择合适的灭火方法。\n\u003Cbr \u002F> 非相关人员应该撤离至安全地方。\n\u003Cbr \u002F> 周围一旦着火：如果安全，移去可移动容器。\n\u003Cbr \u002F> 消防员的特殊防护用具：灭火时，一定要穿戴个人防护用品。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块6. 泄漏应急处理\u003C\u002Fstrong>\n\u003Cbr \u002F> 个人防护措施，防护用具，\n\u003Cb>使用特殊的个人防护用品（针对有毒颗粒的P3过滤式空气呼吸器）。远离溢出物\u002F泄露\u003C\u002Fb>\n\u003Cbr \u002F> 紧急措施：处并处在上风处。\n\u003Cbr \u002F> 泄露区应该用安全带等圈起来，控制非相关人员进入。\n\u003Cbr \u002F> 环保措施：防止进入下水道。\n\u003Cbr \u002F> 控制和清洗的方法和材料：清扫收集粉尘，封入密闭容器。注意切勿分散。附着物或收集物应该立即根据合适的\n\u003Cbr \u002F> 法律法规处置。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块7. 操作处置与储存\u003C\u002Fstrong>\n\u003Cbr \u002F> 处理\n\u003Cbr \u002F> 技术措施：在通风良好处进行处理。穿戴合适的防护用具。防止粉尘扩散。处理后彻底清洗双手\n\u003Cbr \u002F> 和脸。\n\u003Cbr \u002F> 非那西丁\n\u003Cb>修改号码：6\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块7. 操作处置与储存\u003C\u002Fstrong>\n\u003Cbr \u002F> 注意事项：如果可能，使用封闭系统。如果粉尘或浮质产生，使用局部排气。\n\u003Cbr \u002F> 操作处置注意事项：避免所有部位的接触！\n\u003Cbr \u002F> 贮存\n\u003Cbr \u002F> 储存条件：保持容器密闭。存放于凉爽、阴暗处。\n\u003Cbr \u002F> 存放处须加锁。\n\u003Cbr \u002F> 远离不相容的材料比如氧化剂存放。\n\u003Cbr \u002F> 包装材料：依据法律。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块8. 接触控制和个体防护\u003C\u002Fstrong>\n\u003Cbr \u002F> 工程控制：尽可能安装封闭体系或局部排风系统。同时安装淋浴器和洗眼器。\n\u003Cbr \u002F> 个人防护用品\n\u003Cbr \u002F> 　呼吸系统防护：\n\u003Cb>防尘面具，自携式呼吸器（SCBA），供气呼吸器等。使用通过政府标准的呼吸器。依\u003C\u002Fb>\n\u003Cbr \u002F> 据当地和政府法规。\n\u003Cbr \u002F> 　手部防护：防渗手套。\n\u003Cbr \u002F> 　眼睛防护：护目镜。如果情况需要，佩戴面具。\n\u003Cbr \u002F> 　皮肤和身体防护：防渗防护服。如果情况需要，穿戴防护靴。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块9. 理化特性\u003C\u002Fstrong>\n\u003Cbr \u002F> 固体\n\u003Cbr \u002F>\n\u003Cb>外形（20°C）：\u003C\u002Fb>\n\u003Cbr \u002F> 外观：\n\u003Cb>晶体-粉末\u003C\u002Fb>\n\u003Cbr \u002F> 颜色：白色类白色\n\u003Cbr \u002F> 气味：无味\n\u003Cbr \u002F>\n\u003Cb>pH:\u003C\u002Fb>无数据资料\n\u003Cbr \u002F> 熔点：\n\u003Cb>136°C\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>沸点\u002F沸程\u003C\u002Fb>\n\u003Cb>132 °C\u002F0.5kPa\u003C\u002Fb>\n\u003Cbr \u002F> 闪点：无资料\n\u003Cbr \u002F> 爆炸特性\n\u003Cbr \u002F> 　爆炸下限：无资料\n\u003Cbr \u002F> 　爆炸上限：无资料\n\u003Cbr \u002F> 蒸气压：\n\u003Cb>0.4kPa\u002F25°C\u003C\u002Fb>\n\u003Cbr \u002F> 密度：无资料\n\u003Cbr \u002F> 溶解度：\n\u003Cbr \u002F>\n\u003Cb>[水]\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>不溶于(530mg\u002FL, 25°C)\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>[其他溶剂]\u003C\u002Fb>\n\u003Cbr \u002F> 易溶于：嘧啶\n\u003Cbr \u002F> 溶于：\n\u003Cb>丙酮, 氯仿, 甘油\u003C\u002Fb>\n\u003Cbr \u002F> 微溶于：\n\u003Cb>醚, 苯\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>log水分配系数 =\u003C\u002Fb>\n\u003Cb>1.58\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块10. 稳定性和反应性\u003C\u002Fstrong>\n\u003Cbr \u002F> 化学稳定性：一般情况下稳定。\n\u003Cbr \u002F> 危险反应的可能性：未报道特殊反应性。\n\u003Cbr \u002F> 须避免接触的物质\n\u003Cb>氧化剂, 强酸, 强碱, 还原剂\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>危险的分解产物:\u003C\u002Fb>\n\u003Cb>一氧化碳, 二氧化碳, 氮氧化物 (NOx)\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块11. 毒理学信息\u003C\u002Fstrong>\n\u003Cbr \u002F> 急性毒性：\n\u003Cb>orl-rat LD50:1650 mg\u002Fkg\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>ihl-mus LC50:33900 mg\u002Fm3\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>ipr-rat LD50:634 mg\u002Fkg\u003C\u002Fb>\n\u003Cbr \u002F> 非那西丁\n\u003Cb>修改号码：6\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块11. 毒理学信息\u003C\u002Fstrong>\n\u003Cbr \u002F> 对皮肤腐蚀或刺激：无资料\n\u003Cbr \u002F> 对眼睛严重损害或刺激：无资料\n\u003Cbr \u002F> 生殖细胞变异原性：\n\u003Cb>dnd-hmn-oth 1 mmol\u002FL\u002F20H\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>mmo-hmn-lym 1500 mg\u002FL (+S9)\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>mmo-sat 333 ug\u002Fplate (-S9)\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>sce-mus-ipr 165 mg\u002Fkg\u003C\u002Fb>\n\u003Cbr \u002F> 致癌性：\n\u003Cb>orl-hmn TDLo:7300 mg\u002F1Y-C\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>orl-man TDLo:57 g\u002Fkg\u002F47Y-I\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>orl-rat TDLo:572 g\u002Fkg\u002F60W-C\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>orl-wmn TDLo:80 g\u002Fkg\u002F63Y-I\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>IARC =\u003C\u002Fb>\n\u003Cb>1 （对人类致癌）。\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>NTP =\u003C\u002Fb>\n\u003Cb>a（已知致癌物）。\u003C\u002Fb>\n\u003Cbr \u002F> 生殖毒性：无资料\n\u003Cbr \u002F>\n\u003Cb>RTECS 号码:\u003C\u002Fb>\n\u003Cb>AM4375000\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块12. 生态学信息\u003C\u002Fstrong>\n\u003Cbr \u002F> 生态毒性：\n\u003Cbr \u002F> 鱼类：\n\u003Cb>48h LC50:335 ppm (Oryzias latipes)\u003C\u002Fb>\n\u003Cbr \u002F> 甲壳类：无资料\n\u003Cbr \u002F> 藻类：无资料\n\u003Cbr \u002F>\n\u003Cb>残留性 \u002F 降解性：\u003C\u002Fb>\n\u003Cb>8.4 % (by BOD), 22.8 % (by TOC)\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>潜在生物累积 （BCF):\u003C\u002Fb>\n\u003Cb><3 (conc. 0.3 ppm), <30 (conc. 0.03 ppm)\u003C\u002Fb>\n\u003Cbr \u002F> 土壤中移动性\n\u003Cbr \u002F>\n\u003Cb>　log水分配系数：\u003C\u002Fb>\n\u003Cb>1.58\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>　土壤吸收系数 （Koc）：\u003C\u002Fb>\n\u003Cb>170\u003C\u002Fb>\n\u003Cbr \u002F> 　亨利定律\n\u003Cb>2.16 x 10-5\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>constant(PaM3\u002Fmol):\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块13. 废弃处置\u003C\u002Fstrong>\n\u003Cbr \u002F> 如果可能，回收处理。请咨询当地管理部门。建议在可燃溶剂中溶解混合，在装有后燃和洗涤装置的化学焚烧炉中\n\u003Cbr \u002F> 焚烧。废弃处置时请遵守国家、地区和当地的所有法规。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块14. 运输信息\u003C\u002Fstrong>\n\u003Cbr \u002F> 联合国分类：与联合国分类标准不一致\n\u003Cbr \u002F>\n\u003Cb>UN编号：\u003C\u002Fb>未列明\n\u003Cbr \u002F>\n\n\u003Cstrong>模块15. 法规信息\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>《危险化学品安全管理条例》（2002年1月26日国务院发布，2011年2月16日修订）: 针对危险化学品的安全使用、\u003C\u002Fb>\n\u003Cbr \u002F> 生产、储存、运输、装卸等方面均作了相应的规定。\n\u003Cbr \u002F> 非那西丁\n\u003Cb>修改号码：6\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cbr \u002F>\n\n\u003Cstrong> 模块16 - 其他信息 \u003C\u002Fstrong>\n\u003Cbr \u002F>N\u002FA\n\u003Cbr \u002F>\u003Cbr \u002F>\u003Cbr \u002F>\u003Cbr \u002F>\u003Cbr \u002F>\n\u003Cbr \u002F>\n\u003C\u002Ftd>","2026-08-21T07:51:12.859463Z",false,[405,411,417,423,429,435,441,447,453,459,465,471],{"slug":406,"cid":407,"name":408,"nameZh":409,"cas":410},"785896204453023744","J-43882-4","Phenanthridine","菲啶","229-87-8",{"slug":412,"cid":413,"name":414,"nameZh":415,"cas":416},"785883564309745664","J-1312022-4","Di-n-butyl sulfone","二丁砜","598-04-9",{"slug":418,"cid":419,"name":420,"nameZh":421,"cas":422},"785872365274796032","J-1991839-9","D-(+)-Talose","D-(+)-塔洛糖","2595-98-4",{"slug":424,"cid":425,"name":426,"nameZh":427,"cas":428},"785896766087106560","J-1081340-8","D-Galactose","D-半乳糖","59-23-4",{"slug":430,"cid":431,"name":432,"nameZh":433,"cas":434},"785893663988256768","J-1106729-1","1,10-Phenanthroline","1,10-菲罗啉","66-71-7",{"slug":436,"cid":437,"name":438,"nameZh":439,"cas":440},"785889598558441472","J-28214-4","9H-Fluoren-9-amine","9-氨基芴","525-03-1",{"slug":442,"cid":443,"name":444,"nameZh":445,"cas":446},"785876555912974336","J-960136-9","5,6-dihydro-3H-imidazo[2,1-c]-1,2,4-dithiazole-3-thione","代森硫","33813-20-6",{"slug":448,"cid":449,"name":450,"nameZh":451,"cas":452},"785897000599031808","J-46034-4","1-(Cyclohexylmethyl)piperazine","1-环己甲基哌嗪","57184-23-3",{"slug":454,"cid":455,"name":456,"nameZh":457,"cas":458},"785876036330983424","J-11888-7","Saccharin","糖精","81-07-2",{"slug":460,"cid":461,"name":462,"nameZh":463,"cas":464},"785883598057115648","J-1013675-1","Carbazole-d8","咔唑-d8","38537-24-5",{"slug":466,"cid":467,"name":468,"nameZh":469,"cas":470},"785875771490045952","J-1042744-8","1-Hexylpiperazine","1-己基哌嗪","51619-55-7",{"slug":472,"cid":473,"name":474,"nameZh":475,"cas":476},"785881012558106624","J-17869-8","3-Acetylcoumarin","3-乙酰基香豆素","3949-36-8",1794250896184,"zh-CN",[]]