[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"currency-rates":3,"$fyk2oeqxpb7bd":8,"compound-J-28130-4":171,"verified-suppliers-J-28130-4":384},{"rates":4,"source":7},{"USD":5,"CNY":6},1,6.691314,"live",{"rows":9,"total":170,"current":5,"size":145},[10,33,45,60,74,85,96,113,123,135,146,158],{"slug":11,"cid":12,"imgSvg":13,"name":14,"nameZh":15,"cas":16,"formula":17,"iupac":14,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":22,"offersCount":24,"supplierCount":25,"bestOffer":26},"843627791009189888","J-1971488-8","\u002Fimages\u002Fchem_structures_svg\u002F399\u002F65845-61-6.svg","N-Methylcyclohexanamine hydrochloride","N-甲基环己胺盐酸盐","65845-61-6","C7H16ClN","acids","有机酸","Organic Acids","",[23],"In Stock",4,2,{"unitPrice":27,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},2.64,"500g","CNY","China","CN","in-stock",{"slug":34,"cid":35,"imgSvg":36,"name":37,"nameZh":38,"cas":39,"formula":40,"iupac":37,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":41,"offersCount":24,"supplierCount":5,"bestOffer":42},"785882541994283008","J-1323843-4","\u002Fimages\u002Fchem_structures_svg\u002F104\u002F67627-18-3.svg","Potassium indigotrisulfonate","靛蓝三磺酸钾","67627-18-3","C16H7K3N2O11S3",[23],{"unitPrice":43,"pack":44,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},180,"5g",{"slug":46,"cid":47,"imgSvg":48,"name":49,"nameZh":50,"cas":51,"formula":52,"iupac":49,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":56,"offersCount":57,"supplierCount":25,"bestOffer":58},"785889752443260928","J-28559-9","\u002Fimages\u002Fchem_structures_svg\u002F292\u002F15060-55-6.svg","Ammonium tetrathiomolybdate","四硫钼酸铵","15060-55-6","H8MoN2S4","inorganic","无机化合物","Inorganic Chemicals",[23],7,{"unitPrice":59,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},24,{"slug":61,"cid":62,"imgSvg":63,"name":64,"nameZh":65,"cas":66,"formula":67,"iupac":64,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":68,"offersCount":69,"supplierCount":25,"bestOffer":70},"855452191530422272","J-1994428-7","\u002Fimages\u002Fchem_structures_svg\u002F500\u002F16350-96-2.svg","N-benzylcyclohexanamine.hydrochloride","N-苄基环己胺盐酸盐","16350-96-2","C13H20ClN",[23],5,{"unitPrice":71,"pack":72,"currency":29,"origin":73,"originFlag":31,"moq":21,"stock":32},6,"1000g","中国",{"slug":75,"cid":76,"imgSvg":77,"name":78,"nameZh":79,"cas":80,"formula":81,"iupac":78,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":82,"offersCount":25,"supplierCount":25,"bestOffer":83},"785871840001134592","J-982001-0","\u002Fimages\u002Fchem_structures_svg\u002F001\u002F10517-44-9.svg","1,3-Diaminopropane dihydrochloride","1,3-二氨基丙烷二盐酸盐","10517-44-9","C3H12Cl2N2",[23],{"unitPrice":84,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},3.78,{"slug":86,"cid":87,"imgSvg":88,"name":89,"nameZh":90,"cas":91,"formula":92,"iupac":89,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":93,"offersCount":57,"supplierCount":94,"bestOffer":95},"785880365658017792","J-14975-6","\u002Fimages\u002Fchem_structures_svg\u002F262\u002F12003-67-7.svg","Lithium aluminate","氧化铝锂","12003-67-7","AlHLiO2",[23],3,{"unitPrice":94,"pack":28,"currency":29,"origin":73,"originFlag":31,"moq":21,"stock":32},{"slug":97,"cid":98,"imgSvg":99,"name":100,"nameZh":101,"cas":102,"formula":103,"iupac":100,"category":104,"categoryName":105,"categoryEnName":106,"industry":21,"tags":107,"offersCount":108,"supplierCount":108,"bestOffer":109},"785871830249377792","J-6931-9","\u002Fimages\u002Fchem_structures_svg\u002F456\u002F58068-80-7.svg","1-Octanoylbenzotriazole","N-辛酰苯并三唑","58068-80-7","C14H19N3O","aromatics","芳香烃","Aromatic Hydrocarbons",[],0,{"unitPrice":110,"pack":21,"currency":111,"origin":21,"originFlag":21,"moq":21,"stock":112},9007199254740991,"USD","made-to-order",{"slug":114,"cid":115,"imgSvg":116,"name":117,"nameZh":118,"cas":119,"formula":120,"iupac":117,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":121,"offersCount":69,"supplierCount":25,"bestOffer":122},"785871842446413824","J-1960944-3","\u002Fimages\u002Fchem_structures_svg\u002F495\u002F10534-86-8.svg","Hexaamminecobalt(III) nitrate","六氨合钴(III)硝酸盐","10534-86-8","CoH18N9O9",[23],{"unitPrice":71,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},{"slug":124,"cid":125,"imgSvg":126,"name":127,"nameZh":128,"cas":129,"formula":130,"iupac":127,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":131,"offersCount":24,"supplierCount":25,"bestOffer":132},"785871842576437248","J-814544-6","\u002Fimages\u002Fchem_structures_svg\u002F221\u002F12037-42-2.svg","vanadium oxide","氧化钒","12037-42-2","O13V6",[23],{"unitPrice":133,"pack":134,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},112.8,"100g",{"slug":136,"cid":137,"imgSvg":138,"name":139,"nameZh":140,"cas":141,"formula":142,"iupac":139,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":143,"offersCount":57,"supplierCount":5,"bestOffer":144},"785871842647740416","J-1333345-2","\u002Fimages\u002Fchem_structures_svg\u002F479\u002F26490-63-1.svg","COBALT TETRAFLUOROBORATE HEXAHYDRATE","四氟化硼钴水合物","26490-63-1","B2CoF8H12O6",[23],{"unitPrice":145,"pack":134,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},12,{"slug":147,"cid":148,"imgSvg":149,"name":150,"nameZh":151,"cas":152,"formula":153,"iupac":150,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":154,"offersCount":155,"supplierCount":94,"bestOffer":156},"785871842698072064","J-814953-0","\u002Fimages\u002Fchem_structures_svg\u002F432\u002F72259-10-0.svg","Copper(II) tetrafluoroborate hexahydrate","六水合四氟硼酸铜(II)","72259-10-0","B2CuF8H12O6",[23],10,{"unitPrice":157,"pack":28,"currency":29,"origin":21,"originFlag":21,"moq":21,"stock":32},2.6,{"slug":159,"cid":160,"imgSvg":161,"name":162,"nameZh":163,"cas":164,"formula":165,"iupac":162,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":166,"offersCount":25,"supplierCount":5,"bestOffer":168},"785871863254355968","J-1990080-7","\u002Fimages\u002Fchem_structures_svg\u002F149\u002F123333-60-8.svg","Cerium(IV) sulfate hydrate","铈(IV)硫酸盐水合物","123333-60-8","CeH2O9S2",[167],"Made to Order",{"unitPrice":169,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},5.6,3204,{"slug":172,"cid":173,"imgSvg":174,"name":175,"nameZh":175,"cas":176,"formula":177,"iupac":175,"mdl":21,"mw":178,"category":179,"categoryName":180,"categoryEnName":181,"industry":21,"tags":182,"synonyms":183,"properties":191,"ghs":255,"offers":260,"activity":261,"upstream":286,"downstream":287,"customs":288,"safetyRows":301,"toxicity":341,"synthesis":342,"updatedAt":343,"isProhibited":344,"related":345,"__ts":382,"__lang":383,"__slug":173},"785889574017568768","J-28130-4","\u002Fimages\u002Fchem_structures_svg\u002F221\u002F22862-76-6.svg","茴香霉素","22862-76-6","C14H19NO4","265.305","organic","有机化合物","Organic Compounds",[],[184,185,186,187,188,189,190],"回香霉素","梧宁霉素C","茴香霉素(链霉菌属)","茴香霉素(链霉菌素)","茴香霉素(来源于灰色链霉菌)","阿尼霉素","茴香莓素",[192,197,202,207,212,216,220,223,227,231,235,239,243,247,251],{"label":193,"labelZh":194,"value":195,"prop":196},"Melting Point","熔点","140-141ºC","meltingPoint",{"label":198,"labelZh":199,"value":200,"prop":201},"Boiling Point","沸点","398.7±42.0 °C at 760 mmHg","boilingPoint",{"label":203,"labelZh":204,"value":205,"prop":206},"Density","密度","1.2±0.1 g\u002Fcm3","density",{"label":208,"labelZh":209,"value":210,"prop":211},"Flash Point","闪点","194.9±27.9 °C","flashPoint",{"label":213,"labelZh":214,"value":215},"Exact Mass","精确质量","265.131409",{"label":217,"labelZh":218,"value":219},"PSA","其他信息","67.79000",{"label":221,"labelZh":221,"value":222},"LogP","0.42",{"label":224,"labelZh":225,"value":226},"Appearance","外观性状","白色结晶固体",{"label":228,"labelZh":229,"value":230},"Vapor Pressure","蒸汽压","0.0±1.0 mmHg at 25°C",{"label":232,"labelZh":233,"value":234},"Refractive Index","折射率","1.558",{"label":236,"labelZh":237,"value":238},"Storage Conditions","储存条件","放入紧密的贮藏器内，储存在阴凉，干燥的地方",{"label":240,"labelZh":241,"value":242},"Stability","稳定性","常温常压下稳定\n避免接触 强氧化剂",{"label":244,"labelZh":245,"value":246},"Molecular Structure","分子结构","1、 摩尔折射率：70.46\n2、 摩尔体积（cm\n3\n\u002Fmol）：218.6\n3、 等张比容(90.2K)：577.8\n4、 表面张力(dyne\u002Fcm)：48.7\n5、 极化率(10-24cm\n3\n)：27.93",{"label":248,"labelZh":249,"value":250},"Computational Chemistry","计算化学","1、疏水参数计算参考值（XlogP）:0.9\n2、氢键供体数量：2\n3、氢键受体数量：5\n4、可旋转化学键数量:5\n5、互变异构体数量：\n6、拓扑分子极性表面积（TPSA）:67.8\n7、重原子数量：19\n8、表面电荷：0\n9、复杂度：302\n10、同位素原子数量：0\n11、确定原子立构中心数量：3\n12、不确定原子立构中心数量：0\n13、确定化学键立构中心数量：0\n14、不确定化学键立构中心数量：0\n15、共价键单元数量：1",{"label":252,"labelZh":253,"value":254},"Additional Property","更多","1. 性状：长针状结晶。\n2. 密度（g\u002FmL,25\u002F4℃）： 未确定\n3. 相对蒸汽密度（g\u002FmL,空气=1）：未确定\n4. 熔点（ºC）：140～141\n5. 沸点（ºC,常压）：未确定\n6. 沸点（ºC,5.2kPa）：未确定\n7. 折射率：未确定\n8. 闪点（ºC）：未确定\n9. 比旋光度（º，C＝1，甲醇中）：－30°\n10. 自燃点或引燃温度（ºC）：未确定\n11. 蒸气压（kPa,25ºC）：未确定\n12. 饱和蒸气压（kPa,60ºC）：未确定\n13. 燃烧热（KJ\u002Fmol）：未确定\n14. 临界温度（ºC）：未确定\n15. 临界压力（KPa）：未确定\n16. 油水（辛醇\u002F水）分配系数的对数值：未确定\n17. 爆炸上限（%,V\u002FV）：未确定\n18. 爆炸下限（%,V\u002FV）：未确定\n19. 溶解性：溶于水、低级醇、酯、酮和氯仿，微溶于苯、甲苯和己烷。室温时水溶液在很宽的pH范围内稳定。",{"pictogram":256,"signal":257,"hazards":258},"Acute Toxicity","Danger",[259],"H301 — Toxic if swallowed \u002F 吞咽会中毒",[],[262,265,268,271,274,277,280,283],{"key":263,"value":264},"描述","Anisomycin是一种有效的蛋白质合成抑制剂,它通过抑制肽基转移酶或80S核糖体系统干扰蛋白质和DNA合成。",{"key":266,"value":267},"相关类别","信号通路\n>>\n细胞周期\u002FDNA损伤\n>>\nDNA\u002FRNA合成\n研究领域\n>>\n癌症",{"key":269,"value":270},"靶点","DNA synthesis[1]",{"key":272,"value":273},"体外研究","为了检查JNK是否在PC-12细胞中的粘菌素诱导的神经毒性中具有核心作用,在该研究中使用SP600125(JNK的高选择性抑制剂)和Anisomycin(强效激活剂)。为了选择合适的浓度,分别用一系列SP600125(0-80μM)和Anisomycin(0-20μM)处理PC-12细胞24小时。结果显示,SP600125处理以浓度依赖性方式显着降低细胞存活率,在大于20μM的浓度下观察到(p \u003C0.01)。类似地,通过Anisomycin处理(≥8μM)抑制细胞活力(p \u003C0.05)[1]。",{"key":275,"value":276},"体内研究","TNFRp55\u002Fp75的破坏减弱了Anisomycin诱导的心室功能改善。 Anisomycin导致左心室发展压力(LVDP)的改善,其在TNFR p55\u002Fp75破坏的动物中消失。此外,通过删除TNFR p55\u002Fp75消除了野生型动物中的Anisomycin诱导的LVEDP改善。同样地,TNFR p55\u002Fp75的破坏消除了通过预处理Anisomycin引起的速率压力产物(RPP)的回收。与对照野生型小鼠相比,没有使用Anisomycin处理的TNFR p55\u002Fp75 -\u002F-小鼠在心脏功能恢复方面没有显示出差异。野生型和TNFR p55\u002Fp75缺陷小鼠的心率没有显着差异。为了观察Nox2是否参与Anisomycin诱导的心肌保护,用Anisomycin处理Nox2缺陷型小鼠。与野生型小鼠相比,在Nox2 -\u002F-小鼠中消除了在Anisomycin处理的小鼠中LVEDP的改善。此外,在Nox2 -\u002F-小鼠中减轻了用Anisomycin处理的野生型小鼠中RPP的恢复。与野生型对照小鼠相比,没有使用Anisomycin处理的Nox2 -\u002F-小鼠在心脏功能恢复方面没有显示出差异[2]。",{"key":278,"value":279},"细胞实验","将PC-12细胞以1×10 4个细胞\u002F孔的浓度接种于96孔板中，并在37℃，5％CO 2的培养箱中培养至少12小时，然后暴露于不同浓度的SP600125（0- 80μM）或Anisomycin（0-20μM）24小时。随后，将培养基加入20μL5mg\u002F mL MTT工作溶液中，并将板在37℃下温育2小时。除去培养上清液，将甲crystals晶体溶于150μLDMSO中。最后，通过酶标仪在490nm处测量每个孔的吸光度。细胞活力表示为对照组的百分比，设定为100％[1]。",{"key":281,"value":282},"动物实验","小鼠[2]在该研究中使用成年雄性TNFRp55 \u002F p75小鼠，成年雄性野生型C57 \u002F BL和纯合型Nox2  -  \u002F  - 小鼠。将小鼠随机分成六个实验组，进行以下治疗。将动物分为六组：第1组：对照缺血\u002F再灌注，向野生型小鼠注射DMSO（0.1mL）;第2组：Anisomycin +野生型小鼠，野生型小鼠注射Anisomycin（0.1 mg \u002F kg ip）;组3：Anisomycin + TNFR p55 \u002F p75  -  \u002F  - 小鼠，TNFR p55 \u002F 75  -  \u002F  - 小鼠注射Anisomycin（0.1mg \u002F kg ip）;第4组：TNFR p55 \u002F p75  -  \u002F  - 小鼠，TNFR p55 \u002F 75  -  \u002F  - 小鼠未注射Anisomycin;组5：Anisomycin + Nox2  -  \u002F  - 小鼠，Nox2  -  \u002F  - 小鼠注射Anisomycin（0.1mg \u002F kg ip）;和第6组：Nox2  -  \u002F  - 小鼠，Nox2  -  \u002F  - 小鼠未注射Anisomycin。后来（24小时），心脏缺血30分钟，再灌注30分钟[2]。",{"key":284,"value":285},"参考文献","[1].\nLu Z, et al. Colistin-induced autophagy and apoptosis involves the JNK-Bcl2-Bax signaling pathway and JNK-p53-ROS positive feedback loop in PC-12 cells.\n[2].\nZhao TC, et al. Disruption of Nox2 and TNFRp55\u002Fp75 eliminates cardioprotection induced by Anisomycin. Am J Physiol Heart Circ Physiol. 2012 Nov 15;303(10):H1263-72.",[],[],[289,292,295,298],{"key":290,"value":291},"海关编码","2933990090",{"key":293,"value":294},"中文概述","2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%",{"key":296,"value":297},"申报要素","品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期",{"key":299,"value":300},"Summary","2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%",[302,305,307,310,313,316,319,322,325,328,331,334,337,340],{"key":303,"value":304},"符号","GHS06",{"key":306,"value":257},"信号词",{"key":308,"value":309},"危害声明","H301",{"key":311,"value":312},"警示性声明","P301 + P310",{"key":314,"value":315},"个人防护装备","Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges",{"key":317,"value":318},"危害码 (欧洲)","T: Toxic;",{"key":320,"value":321},"风险声明 (欧洲)","R25",{"key":323,"value":324},"安全声明 (欧洲)","45-36-26",{"key":326,"value":327},"危险品运输编码","UN 3462 6",{"key":329,"value":330},"WGK德国","3",{"key":332,"value":333},"RTECS号","BZ9800000",{"key":335,"value":336},"包装等级","III",{"key":338,"value":339},"危险类别","6.1(b)",{"key":290,"value":291},"\u003Ctd>\n\n\u003Cp>\u003Cstrong>茴香霉素毒理学数据:\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Cp>\u003C\u002Fp>\u003Cp> \u003Cbr \u002F> \u003C\u002Fp>\n\u003Cp>\u003C\u002Fp>\n\u003Cp>\u003Cstrong>茴香霉素生态学数据:\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Cp>\u003C\u002Fp>\u003Cp> \u003Cbr \u002F> \u003C\u002Fp>\n\u003Cp>\u003C\u002Fp>\n\u003Cp>\u003Ca href=\"\u002Fen\u002Fcas\u002F22862-76-6_671915.html#duXinDiv\">茴香霉素毒性英文版\u003C\u002Fa>\u003C\u002Fp>\n\n\u003C\u002Ftd>","\u003Cp> \u003Cbr \u002F> \u003C\u002Fp>","2026-08-21T07:51:12.859463Z",false,[346,352,358,364,370,376],{"slug":347,"cid":348,"name":349,"nameZh":350,"cas":351},"785895059647107072","J-39988-7","Maneb","代森锰","12427-38-2",{"slug":353,"cid":354,"name":355,"nameZh":356,"cas":357},"785897759302488064","J-47789-5","Potassium 5-mercapto-3-phenyl-1,3,4-thiadiazole-2-thione","铋试剂II","6336-51-2",{"slug":359,"cid":360,"name":361,"nameZh":362,"cas":363},"785896201537982464","J-1513803-1","5-(4-Dimethylaminobenzylidene)rhodanine","对二甲氨基苄罗丹宁","536-17-4",{"slug":365,"cid":366,"name":367,"nameZh":368,"cas":369},"785881280762875904","J-18554-3","Sodium carboxymethyl cellulose","羧甲基纤维素钠","9004-32-4",{"slug":371,"cid":372,"name":373,"nameZh":374,"cas":375},"785882575020232704","J-4798-8","m-Methyl red","间甲基红","20691-84-3",{"slug":377,"cid":378,"name":379,"nameZh":380,"cas":381},"785894611636719616","J-38269-8","Methyl Red","甲基红","493-52-7",1792644982087,"zh-CN",[]]